Studies on calcium release channels from sarcoplasmic reticulum in planar bilayers 脂質平面膜による筋小胞体カルシウム放出チャネルの研究
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Bibliographic Information
- Title
-
Studies on calcium release channels from sarcoplasmic reticulum in planar bilayers
- Other Title
-
脂質平面膜による筋小胞体カルシウム放出チャネルの研究
- Author
-
丁, 建
- Author(Another name)
-
テイ, ケン
- University
-
大阪大学
- Types of degree
-
博士 (理学)
- Grant ID
-
甲第5656号
- Degree year
-
1996-03-25
Note and Description
博士論文
Table of Contents
- CONTENTS / (0003.jp2)
- Abbreviations / p1 (0005.jp2)
- Names of multiple conductance states of a Ca²⁺release channel / p2 (0006.jp2)
- Abstract / p3 (0007.jp2)
- Introduction / p5 (0009.jp2)
- Material and Method / p11 (0015.jp2)
- 1.Reagents / p11 (0015.jp2)
- 2.Preparation for HSR / p11 (0015.jp2)
- 3.Purification of RyR / p11 (0015.jp2)
- 4.Bilayer system and planar bilayer measurement / p12 (0016.jp2)
- 5.Protein concentration determination / p22 (0026.jp2)
- 6.Calculation of the free Ca²⁺concentration / p22 (0026.jp2)
- Result / p23 (0027.jp2)
- 1.Effect of ATP and ruthenium red to rapid fluctuation current / p23 (0027.jp2)
- 2.Slowly and rapidly fluctuating currents through RyR complex / p23 (0027.jp2)
- 3.Multiple conductance states in one small pore of RyR complex / p27 (0031.jp2)
- 4.Multiple conductance states in four small pores of RyR complex / p29 (0033.jp2)
- 5.Multiple conductance states of slow fluctuation current / p33 (0037.jp2)
- 6.DIDS effect to the current through RyR complex / p41 (0045.jp2)
- 7.Rapid fluctuation current with a high conductance state / p41 (0045.jp2)
- Discussion / p44 (0048.jp2)
- 1.Both rapid and slow fluctuation currents were the current through RyR complex / p44 (0048.jp2)
- 2.RyR complex has two different configurations / p44 (0048.jp2)
- 3.Slowly fluctuating current through RyR and the large pore in series / p45 (0049.jp2)
- 4.Pore fusion assumption and ryanodine induced sub-block states / p50 (0054.jp2)
- 5.Model of the states in the fused big pore / p54 (0058.jp2)
- 6.Multiple conductance states of RyR complex / p57 (0061.jp2)
- 7.High conductance states and glucose permeation / p59 (0063.jp2)
- 8.Ryanodine binding and ryanodine-induced responses / p61 (0065.jp2)
- 9.Open-lock behavior and DIDS effect / p62 (0066.jp2)
- 10.Rapid fluctuation current with large conductance(2500pS) / p64 (0068.jp2)
- 11.Selectivity of RyR / p64 (0068.jp2)
- References / p66 (0070.jp2)
- Acknowledgement / p72 (0076.jp2)
