Nucleic acid dynamics and furanose ring pseudo-rotation 核酸の動力学と糖の擬回転
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著者
書誌事項
- タイトル
-
Nucleic acid dynamics and furanose ring pseudo-rotation
- タイトル別名
-
核酸の動力学と糖の擬回転
- 著者名
-
冨本, 昌樹
- 著者別名
-
トミモト, マサキ
- 学位授与大学
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京都大学
- 取得学位
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博士 (理学)
- 学位授与番号
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甲第6287号
- 学位授与年月日
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1996-03-23
注記・抄録
博士論文
目次
- 論文目録 / (0001.jp2)
- TABLE OF CONTENTS / p1 (0007.jp2)
- ACKNOWLEDGMENT / p1 (0009.jp2)
- ABSTRACT / p3 (0011.jp2)
- INTRODUCTION / p5 (0013.jp2)
- METHODS / p11 (0019.jp2)
- (1)Pseudo-rotation / p11 (0019.jp2)
- 1.1 Cyclopentane / p11 (0019.jp2)
- 1.2 Tetrahydrofuran / p28 (0036.jp2)
- 1.3 Ribose and Deoxyribose / p35 (0043.jp2)
- (2)Algorithm for computation / p42 (0050.jp2)
- 2.1 Variables / p42 (0050.jp2)
- 2.2 Optimization / p44 (0052.jp2)
- (3)Normal mode analysis / p47 (0055.jp2)
- 3.1 Molecules / p47 (0055.jp2)
- 3.2 Conformational space and energy function / p48 (0056.jp2)
- 3.3 Normal mode analysis / p49 (0057.jp2)
- 3.4 Atomic motion of thermal equilibrium / p50 (0058.jp2)
- 3.5 Pseudo-rotation in normal mode analysis / p51 (0059.jp2)
- 3.6 Relation between normal modes / p52 (0060.jp2)
- 3.7 Fluctuations of substrate / p52 (0060.jp2)
- RESULTS / p54 (0062.jp2)
- (1)Pseudo-rotation / p54 (0062.jp2)
- 1.1 Cyclopentane / p54 (0062.jp2)
- 1.2 Tetrahydrofuran / p54 (0062.jp2)
- 1.3 Ribose and deoxyribose / p56 (0064.jp2)
- (2)Hammerhead ribozyme / p57 (0065.jp2)
- 2.1 Minimum energy conformations / p57 (0065.jp2)
- 2.2 Cleavage site / p59 (0067.jp2)
- 2.3 Frequency distributions / p60 (0068.jp2)
- 2.4 Fluctuations of main-chain heavy atoms / p61 (0069.jp2)
- 2.5 Fluctuations of main-chain dihedral angles / p62 (0070.jp2)
- 2.6 Dynamics of substrate / p63 (0071.jp2)
- 2.7 Relation between normal modes / p63 (0071.jp2)
- 2.8 Dynamics of ribozyme / p64 (0072.jp2)
- 2.9 Conformational rearrangement for catalysis / p66 (0074.jp2)
- CONCLUSION / p68 (0076.jp2)
- REFERENCES / p72 (0080.jp2)
- TABLES / p76 (0084.jp2)
- FIGURE LEGENDS / p83 (0091.jp2)
- FIGURES / p93 (0101.jp2)
- Normal Mode Analysis of a Nucleic Acid with Flexible Furanose Rings in Dihedral Angle Space / (0192.jp2)