Neoglycoconjugates of biological interests : design, synthesis, and application 生物学的に重要な擬似複合糖質 : 設計、合成、及び応用

この論文をさがす

著者

    • 王, 来曦 ワン, ライシ

書誌事項

タイトル

Neoglycoconjugates of biological interests : design, synthesis, and application

タイトル別名

生物学的に重要な擬似複合糖質 : 設計、合成、及び応用

著者名

王, 来曦

著者別名

ワン, ライシ

学位授与大学

北海道大学

取得学位

博士 (理学)

学位授与番号

乙第4900号

学位授与年月日

1996-03-25

注記・抄録

博士論文

目次

  1. Table of Contents / p1 (0004.jp2)
  2. Summary of the thesis / p1 (0006.jp2)
  3. Introduction / p5 (0008.jp2)
  4. Chapter1 Studies on the Chemical Synthesis of N-Acetyl-Thiochitooligosaccharides / p21 (0016.jp2)
  5. 1.1 Introduction / p21 (0016.jp2)
  6. 1.2 Synthesis of methyl N,N′-diacetyl-β-thiochitobioside and the acetolysis of its peracetate / p24 (0018.jp2)
  7. 1.3 Analysis of by-products from the acetolysate / p29 (0020.jp2)
  8. 1.4 Synthesis of methyl N,N'-diacetyl-α-thiochitobioside and the acetolysis of its peracetate / p32 (0022.jp2)
  9. 1.5 Comparative study on the acetolysis of methyl 2-acetamido-3,4,6-tri-Ο-acetyl-2-deoxy-α-and β-D-glucopyranosides / p34 (0023.jp2)
  10. 1.6 Extension of sugar chain to higher thiochitooligosaccharides / p36 (0024.jp2)
  11. 1.7 Experimental section / p47 (0029.jp2)
  12. 1.8 References / p69 (0040.jp2)
  13. Chapter2 4-MethylumbeIIiferyl N,N'-Diacetyl-4-Thiochitobioside and N,N',N''-Triacetyl-4,4'-Dithiochitotrioside: Preparation and Potential Application in Chitinase Research / p72 (0042.jp2)
  14. 2.1 Introduction / p73 (0042.jp2)
  15. 2.2 Design of specific, fluorescent substrates / p76 (0044.jp2)
  16. 2.3 Synthesis of 4-methylumbelliferyl N,N'-diacetyl-4-thiochitobioside and N,N',N''-triacetyl-4,4'-dithiochitotrioside / p77 (0044.jp2)
  17. 2.4 Experimental section for substrate synthesis / p79 (0045.jp2)
  18. 2.5 Behaviour of the synthetic substrates toward the chitinase from streptomyces griseus / p88 (0050.jp2)
  19. 2.6 Behaviour of the synthetic substrates toward the chitodextrinase from vibrio furnissii / p91 (0051.jp2)
  20. 2.7 Summary / p92 (0052.jp2)
  21. 2.8 References / p109 (0060.jp2)
  22. Chapter3 Total Chemical Synthesis of the Nodulation Factor Involved in Rhizobium meliloti-Legume Symbiosis / p111 (0061.jp2)
  23. 3.1 Introduction / p111 (0061.jp2)
  24. 3.2 Retrosynthetic design of the target molecule / p113 (0062.jp2)
  25. 3.3 Preparation of monosaccharide synthons / p114 (0063.jp2)
  26. 3.4 Synthesis of the disaccharide glycosyl donor and acceptor / p117 (0064.jp2)
  27. 3.5 Construction of the tetrasaccharide skeleton / p120 (0066.jp2)
  28. 3.6 Synthesis of the fatty acid chain present in NodRm-IV(S) / p122 (0067.jp2)
  29. 3.7 Total synthesis of the target NodRm-IV(S) / p123 (0067.jp2)
  30. 3.8 Recent progresses in the characterization of nodulation factors and their chemical synthesis / p124 (0068.jp2)
  31. 3.9 Experimental section / p128 (0070.jp2)
  32. 3.10 References / p147 (0079.jp2)
  33. Chapter4 A Strategy for the Synthesis of High-Mannose-Type Neoglycopeptides / p150 (0081.jp2)
  34. 4.1 Introduction / p151 (0081.jp2)
  35. 4.2 The target molecule and the synthetic strategy / p153 (0082.jp2)
  36. 4.3 Synthesis of N⁴-[C-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-methyl]-L-asparagine (GlcNAc-CH₂-Asn) / p154 (0083.jp2)
  37. 4.4 Incorporation of GlcNAc-CH₂-Asn into a pentapeptide / p158 (0085.jp2)
  38. 4.5 Enzymatic Transfer of a Man₉GlcNAc residue to the synthetic C-glycopentapeptide / p161 (0086.jp2)
  39. 4.6 Experimental Section / p165 (0089.jp2)
  40. 4.7 References / p175 (0094.jp2)
  41. Chapter5 The Fluorometric Assay of Ceramide Glycanase with 4-Methylumbelliferyl β-D-Lactoside Derivatives / p177 (0095.jp2)
  42. 5.1 Introduction / p178 (0096.jp2)
  43. 5.2 Design of simple,potential ceramide glycanase substrates / p179 (0096.jp2)
  44. 5.3 Synthesis of 4-methylumbelliferyl lactoside derivatives / p180 (0097.jp2)
  45. 5.4 Synthesis of 4-methylumbelliferyl cellobioside derivatives / p182 (0098.jp2)
  46. 5.5 Experimental section for the synthesis of the substrates / p184 (0099.jp2)
  47. 5.6 Assay of ceramide glycanases using synthetic substrates / p199 (0106.jp2)
  48. 5.7 Discussion / p201 (0107.jp2)
  49. 5.8 References / p207 (0110.jp2)
  50. Acknowledgements / p209 (0111.jp2)
  51. List of Publications / p210 (0112.jp2)
0アクセス

各種コード

  • NII論文ID(NAID)
    500000132967
  • NII著者ID(NRID)
    • 8000000967543
  • DOI(NDL)
  • NDL書誌ID
    • 000000297281
  • データ提供元
    • NDL-OPAC
    • NDLデジタルコレクション
ページトップへ