Crystal structure determination of Escherichia coli polyamine binding protein and molecular mechanism of polyamine binding 大腸菌ポリアミン結合蛋白質の結晶構造解析とポリアミン結合の分子機構
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著者
書誌事項
- タイトル
-
Crystal structure determination of Escherichia coli polyamine binding protein and molecular mechanism of polyamine binding
- タイトル別名
-
大腸菌ポリアミン結合蛋白質の結晶構造解析とポリアミン結合の分子機構
- 著者名
-
杉山, 成
- 著者別名
-
スギヤマ, シゲル
- 学位授与大学
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大阪大学
- 取得学位
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博士 (工学)
- 学位授与番号
-
乙第7238号
- 学位授与年月日
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1997-05-23
注記・抄録
博士論文
目次
- CONTENTS / p1 (0004.jp2)
- Chapter1 General Introduction / p1 (0006.jp2)
- 1.1 Polyamines and Anti-Cancer Drugs / p2 (0007.jp2)
- 1.2 Cell Membranes / p3 (0007.jp2)
- 1.3 Active Transport Systems / p4 (0008.jp2)
- 1.4 Substrate Binding Proteins / p6 (0009.jp2)
- 1.5 Polyamine Binding Proteins / p7 (0009.jp2)
- References / p9 (0010.jp2)
- Chapter2 Crystallization and Preliminary X-ray Analysis of the Primary Receptor (PotD) of the Polyamine Transport System in Escherichia coli. / p11 (0011.jp2)
- 2.1 Abstract / p12 (0012.jp2)
- 2.2 Introduction / p13 (0012.jp2)
- 2.3 Crystallization and X-ray Diffraction / p14 (0013.jp2)
- References / p21 (0016.jp2)
- Chapter3 Crystal Structure of PotD, the Primary Receptor of the Polyamine Transport System in Escherichia coli. / p23 (0017.jp2)
- 3.1 Abstract / p24 (0018.jp2)
- 3.2 Introduction / p25 (0018.jp2)
- 3.3 Materials and methods / p26 (0019.jp2)
- 3.4 Results / p30 (0021.jp2)
- 3.5 Discussion / p39 (0025.jp2)
- References / p45 (0028.jp2)
- Chapter4 Spermidine-preferential Uptake System in Escherichia coli Identification of Amino Acids Involved in Polyamine Binding in PotD Protein / p49 (0030.jp2)
- 4.1 Abstract / p50 (0031.jp2)
- 4.2 Introduction / p51 (0031.jp2)
- 4.3 Materials and methods / p52 (0032.jp2)
- 4.4 Results / p55 (0033.jp2)
- 4.5 Discussion / p62 (0037.jp2)
- References / p66 (0039.jp2)
- Chapter5 The 1.8 Å X-ray Structure of the Escherichia coli PotD Protein complexed with Spermidine and the mechanism of polyamine binding / p69 (0040.jp2)
- 5.1 Abstract / p70 (0041.jp2)
- 5.2 Introduction / p71 (0041.jp2)
- 5.3 Materials and methods / p72 (0042.jp2)
- 5.4 Results and Discussion / p75 (0043.jp2)
- References / p90 (0051.jp2)
- Chapter6 Concluding Remarks / p93 (0052.jp2)
- List of Publications / p99 (0055.jp2)
- Acknowledgements / p101 (0056.jp2)
