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Biological studies on a new antibiotic, KRM-1648

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著者

    • 細江, 和典 ホソエ, カズノリ

書誌事項

タイトル

Biological studies on a new antibiotic, KRM-1648

著者名

細江, 和典

著者別名

ホソエ, カズノリ

学位授与大学

岐阜大学

取得学位

博士 (農学)

学位授与番号

乙第10号

学位授与年月日

1997-03-14

注記・抄録

博士論文

目次

  1. 論文目録 / (0001.jp2)
  2. Contents / (0009.jp2)
  3. Abbreviations / p1 (0007.jp2)
  4. Chapter1.Introduction / p1 (0011.jp2)
  5. Chapter2.Discovery of a new rifamycin derivative KRM and its antimicrobial activities / p7 (0017.jp2)
  6. Section1.Discovery of KRM / p7 (0017.jp2)
  7. Introduction / p7 (0017.jp2)
  8. Materials and Methods / p8 (0018.jp2)
  9. Results and Discussion / p13 (0023.jp2)
  10. Summary / p21 (0031.jp2)
  11. Section2.Antimicrobial activity of KRM / p22 (0032.jp2)
  12. Introduction / p22 (0032.jp2)
  13. Materials and Methods / p22 (0032.jp2)
  14. Results / p25 (0035.jp2)
  15. Discussion / p34 (0044.jp2)
  16. Summary / p37 (0047.jp2)
  17. Section3.Mechanism of action / p38 (0048.jp2)
  18. Introduction / p38 (0048.jp2)
  19. Materials and Methods / p38 (0048.jp2)
  20. Results and Discussion / p43 (0053.jp2)
  21. Summary / p49 (0059.jp2)
  22. Chapter3.Development of analytical methods for KRM and its metabolite in biological samples in rats / p50 (0060.jp2)
  23. Introduction / p50 (0060.jp2)
  24. Materials and Methods / p51 (0061.jp2)
  25. Results and Discussion / p55 (0065.jp2)
  26. Summary / p62 (0072.jp2)
  27. Chapter4.Identification and antimicrobial activity of urinary metabolites of KRM in dogs / p64 (0074.jp2)
  28. Introduction / p64 (0074.jp2)
  29. Materials and Methods / p64 (0074.jp2)
  30. Results and Discussion / p68 (0078.jp2)
  31. Summary / p79 (0089.jp2)
  32. Chapter5.Pharmacokinetics of KRM in rats and dogs / p80 (0090.jp2)
  33. Introduction / p80 (0090.jp2)
  34. Materials and Methods / p82 (0092.jp2)
  35. Results / p87 (0097.jp2)
  36. Discussion / p99 (0109.jp2)
  37. Summary / p102 (0112.jp2)
  38. Chapter6.In vitro metabolism of KRM by animal and human liver microsome,whole blood and expressed human CYP3A isoform / p103 (0113.jp2)
  39. Introduction / p103 (0113.jp2)
  40. Materials and Methods / p104 (0114.jp2)
  41. Results / p108 (0118.jp2)
  42. Discussion / p114 (0124.jp2)
  43. Summary / p115 (0125.jp2)
  44. Chapter.7.General discussion / p117 (0127.jp2)
  45. Acknowledgments / p124 (0134.jp2)
  46. References / p125 (0135.jp2)
3アクセス

各種コード

  • NII論文ID(NAID)
    500000154916
  • NII著者ID(NRID)
    • 8000001107874
  • DOI(NDL)
  • NDL書誌ID
    • 000000319230
  • データ提供元
    • 機関リポジトリ
    • NDL-OPAC
    • NDLデジタルコレクション
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