Studies on mofified functions of human antibodies via glycosylation on the light variablle region 抗体可変領域の糖鎖修飾によるヒト抗体の機能改変に関する研究

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著者

    • 金, 知延 キム, ジヨン

書誌事項

タイトル

Studies on mofified functions of human antibodies via glycosylation on the light variablle region

タイトル別名

抗体可変領域の糖鎖修飾によるヒト抗体の機能改変に関する研究

著者名

金, 知延

著者別名

キム, ジヨン

学位授与大学

九州大学

取得学位

博士(農学)

学位授与番号

甲第4769号

学位授与年月日

1999-03-25

注記・抄録

博士論文

目次

  1. CONTENTS / p1 (0003.jp2)
  2. Chapter1.General Introduction / p1 (0009.jp2)
  3. Chapter 2.The Effect Of Various Monosaccharides In The Medium On The Molecular Characteristics Of Antibody Culturing Human-Human Hybridomas / p8 (0016.jp2)
  4. 1.Introdution / p8 (0016.jp2)
  5. 2.Materials and methods / p9 (0017.jp2)
  6. 3.Results / p12 (0020.jp2)
  7. 4.Discussion / p26 (0034.jp2)
  8. 5.Conclusion / p29 (0037.jp2)
  9. Chapter 3.The Effect Of Various Polysaccharides In The Medium On The Molecular Characteristics Of Antibody Culturing Of Human-Human Hybridomas / p31 (0039.jp2)
  10. 1.Introduction / p31 (0039.jp2)
  11. 2.Materials and methods / p32 (0040.jp2)
  12. 3.Results / p34 (0042.jp2)
  13. 4.Discussion / p38 (0046.jp2)
  14. 5.Conclusion / p41 (0049.jp2)
  15. Chapter 4.Metabolic Labeling Of Carbohydrate On The Light Chain Of Antibody Produced From The Medium Containing Differed Monosaccharides / p43 (0051.jp2)
  16. 1.Introduction / p43 (0051.jp2)
  17. 2.Materials and methods / p44 (0052.jp2)
  18. 3.Results / p45 (0053.jp2)
  19. 4.Discussion / p45 (0053.jp2)
  20. 5.Conclusion / p48 (0056.jp2)
  21. Chapter.5.Characterization Of Carbohydrate Chain On The Light Chain Of HB4C5 Antibody Produced In Various Carbon Source Containing Medium / p50 (0058.jp2)
  22. 1.Introduction / p50 (0058.jp2)
  23. 2.Materials and methods / p51 (0059.jp2)
  24. 3.Results / p52 (0060.jp2)
  25. 4.Discussion / p55 (0063.jp2)
  26. 5.Conclusion / p60 (0068.jp2)
  27. Chapter 6.Expressions Of Glycosyltransferases / p62 (0070.jp2)
  28. 1.Introduction / p62 (0070.jp2)
  29. 2.Materials and methods / p64 (0072.jp2)
  30. 3.Results / p76 (0084.jp2)
  31. 4.Discussion / p76 (0084.jp2)
  32. 5.Conclusion / p86 (0094.jp2)
  33. Chapter 7.Sequence Analysis Of The Light Chain Variable Region Of The Human Antibody Produced By Culturing In Various Carbon Sources Containing Medium / p88 (0096.jp2)
  34. 1.Introduction / p88 (0096.jp2)
  35. 2.Materials and methods / p89 (0097.jp2)
  36. 3.Results / p91 (0099.jp2)
  37. 4.Discussion / p95 (0103.jp2)
  38. 5.Conclusion / p96 (0104.jp2)
  39. Chapter 8.High Density Culture Of Hybridoma Cells In Cell Cultivation System / p98 (0106.jp2)
  40. 1.Introduction / p98 (0106.jp2)
  41. 2.Materials and methods / p100 (0108.jp2)
  42. 3.Results / p102 (0110.jp2)
  43. 4.Discussion / p105 (0113.jp2)
  44. 5.Conclusion / p110 (0118.jp2)
  45. Chapter 9.Glycosylation Of Various Hybridoma Cells Introduced Monoclonal Antibody HB4C5 Light Chain / p111 (0119.jp2)
  46. 1.Introduction / p111 (0119.jp2)
  47. 2.Materials and methods / p113 (0121.jp2)
  48. 3.Results / p116 (0124.jp2)
  49. 4.Discussion / p126 (0134.jp2)
  50. 5.Conclusion / p130 (0138.jp2)
  51. Chapter10.General Conclusion / p131 (0139.jp2)
  52. ACKNOWLEDGMENT / p136 (0144.jp2)
  53. REFERENCE / p137 (0145.jp2)
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各種コード

  • NII論文ID(NAID)
    500000171745
  • NII著者ID(NRID)
    • 8000000172019
  • DOI(NDL)
  • NDL書誌ID
    • 000000336059
  • データ提供元
    • NDL-OPAC
    • NDLデジタルコレクション
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