Modifications of μ-opioid receptor agonist-induced several pharmacological actions by diabetes in mice : possible involvement of protein kinase C and intracellular calcium

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著者

    • 大澤, 匡弘 オオサワ, マサヒロ

書誌事項

タイトル

Modifications of μ-opioid receptor agonist-induced several pharmacological actions by diabetes in mice : possible involvement of protein kinase C and intracellular calcium

著者名

大澤, 匡弘

著者別名

オオサワ, マサヒロ

学位授与大学

星薬科大学

取得学位

博士(薬学)

学位授与番号

甲第72号

学位授与年月日

1999-03-13

注記・抄録

博士論文

1998年度

目次

  1. Table of Contents / (0004.jp2)
  2. General Introduction / p1 (0006.jp2)
  3. Chapter1 Modification of μ-opioid receptor-mediated pharmacological action by diabetes in mice:possible involvement of protein kinase C and intracellular calcium / p12 (0012.jp2)
  4. Introduction / p13 (0013.jp2)
  5. Experiment1-1:Effects of diabetes on the morphine-induced Straub tail reaction in mice. / p16 (0014.jp2)
  6. Experiment1-2:Possible involvement of protein kinase C in the attenuation of the morphine-induced Straub tail reaction in diabetic mice / p20 (0016.jp2)
  7. Experiment1-3:Possible involvement of protein kinase C in the attenuation of DAMGO-induced antinociception in diabetic mice. / p26 (0019.jp2)
  8. Experiment1-4:Role of intracellular calcium in modification of μ- and δ-opioid receptor-mediated antinociception by diabetes in mice. / p34 (0023.jp2)
  9. Discussion / p46 (0029.jp2)
  10. Chapter2 Modification of naloxone-precipitated withdrawal syndrome by diabetes in mice:possible involvement of protein kinase C and intracellular calcium / p54 (0033.jp2)
  11. Introduction / p55 (0034.jp2)
  12. Experiment2-1:Modification of development of morphine dependence by diabetes / p61 (0037.jp2)
  13. Experiment2-2:Effect of diabetes on the morphine-induced inhibition of gastrointestinal transit. / p68 (0040.jp2)
  14. Experiment2-3:Role of noradrenergic functions in the modification of naloxone-precipitated withdrawal jumping in morphine-dependent mice by diabetes / p73 (0043.jp2)
  15. Experiment2-4:Modification of the expression of naloxone-precipitated withdrawal signs in morphine-dependent mice by diabetes:possible involvement of protein kinase C. / p78 (0046.jp2)
  16. Experiment2-5:Role of intracellular calcium on the modulation of naloxone-precipitated withdrawal jumping in morphine-dependent mice by diabetes. / p89 (0051.jp2)
  17. Discussion / p96 (0055.jp2)
  18. Chapter3 Modification of reinforcing effect of several addictive drugs by diabetes in mice / p106 (0060.jp2)
  19. Introduction / p107 (0061.jp2)
  20. Experiment3-1:Modification of morphine-induced place preference by diabetes / p111 (0063.jp2)
  21. Experiment3-2:Effects of diabetes on methamphetamine-induced place preference in mice. / p123 (0069.jp2)
  22. Experiment3-3:Effects of streptozotocin-induced diabetes on place conditioning action of cocaine in mice / p131 (0073.jp2)
  23. Discussion / p135 (0075.jp2)
  24. Conclusion / p142 (0078.jp2)
  25. Acknowledgements / p147 (0081.jp2)
  26. References / p148 (0081.jp2)
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各種コード

  • NII論文ID(NAID)
    500000172584
  • NII著者ID(NRID)
    • 8000000172860
  • DOI(NDL)
  • 本文言語コード
    • eng
  • NDL書誌ID
    • 000000336898
  • データ提供元
    • 機関リポジトリ
    • NDL-OPAC
    • NDLデジタルコレクション
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