書誌事項
- タイトル別名
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- CLINICAL COURSE OF NONHEMOLYTIC TRANSFUSION REACTIONS
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Recipients who experienced severe nonhemolytic transfusion reactions (NHTRs) were analyzed with regard to their main clinical symptoms during and after transfusion in 44 national university hospitals in Japan. From 1999 through 2001, we received reports of 56 cases of severe NHTRs. Patient signs and symptoms varied, but dyspnea, decreased blood pressure, and wheals were the most common. Thirty-three (59%) of 56 cases were associated with platelet transfusion. Twenty-one (38%) cases had multiple transfusion reactions. In all 56 cases, the patient's serum was screened for anti-plasma protein antibodies and anti-HLA antibodies by the laboratory of the Japanese Red Cross Blood Center, but only 39 (70%) of 56 cases were specimens of the units of blood products transfused. Three of 56 cases resulted in death and 2 of these 3 reported deaths resulted from transfusion-related acute lung injury (TRALI). Most reactions seemed to be allergic in origin. However, other causes of reactions could not be ruled out because of the lack of blood samples from the blood products transfused. It is important to create a management system for transfusion reactions and to continue research into TRALI.
収録刊行物
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- 日本輸血学会雑誌
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日本輸血学会雑誌 49 (4), 553-558, 2003
一般社団法人 日本輸血・細胞治療学会
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詳細情報 詳細情報について
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- CRID
- 1390001204909380864
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- NII論文ID
- 130003707058
- 50000299658
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- NII書誌ID
- AN00198368
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- ISSN
- 18838383
- 05461448
- http://id.crossref.org/issn/05461448
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可