Temperature Dependence in Proliferation of Tetraploid Meth-A Cells in Comparison with the Parent Diploid Cells.
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- Fujikawa-Yamamoto Kohzaburo
- Division of Basic Science, Research Institute of Medical Science, Kanazawa Medical University
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- Wang Shiyong
- Division of Basic Science, Research Institute of Medical Science, Kanazawa Medical University
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- Yamagishi Hiroko
- Division of Basic Science, Research Institute of Medical Science, Kanazawa Medical University
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- Miyagoshi Minoru
- Division of Basic Science, Research Institute of Medical Science, Kanazawa Medical University
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The temperature dependency for the growth of tetraploid Meth-A cells established from diploid cells was examined in comparison with the parent diploid cells. Proliferation of the tetraploid cells was markedly suppressed below 35°C. At above 40°C, both the diploid and tetraploid Meth-A cells ceased growing. Flow cytometry (FCM) analysis showed that the hyperploid cell fraction increased in the tetraploid Meth-A cell population at low temperatures. The fluidity of cell membranes at different temperatures was measured by means of electron spin resonance (ESR), and it was almost the same between the diploid and tetraploid Meth-A cells. It was suggested that the decreased proliferation below 35°C of the tetraploid Meth-A cells might be due to the increased volume of the cells.
収録刊行物
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- Cell Structure and Function
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Cell Structure and Function 26 (5), 263-269, 2001
日本細胞生物学会
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詳細情報 詳細情報について
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- CRID
- 1390001204697134208
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- NII論文ID
- 50001026591
- 130004137400
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- NII書誌ID
- AA0060007X
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- COI
- 1:CAS:528:DC%2BD38XhtFSjurc%3D
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- ISSN
- 13473700
- 03867196
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- NDL書誌ID
- 6039772
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- PubMed
- 11831358
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可