グリセロール静注試験  判定法および経口法との相違点

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  • The intravenously administered glycerol test in meniere's disease.

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Glycerol test was performed in 182 ears with definite and suspected Meniere's disease in about 8 years. Intravenous administration of 10% glycerol (500ml) for 2 hours was adopted instead of oral administration. Various criteria of glycerol test have been proposed since Klockhoff and Lindblom pablished their first report in 1966. We used only pure tone audiometry and proposed an adequate criteria in our new method, and also discussed the difference between oral and intravenous administration of glycerol from view points of blood concentration of glycerol, serum osmorality and side effects.<br>From our clinical observations, it was concluded that the intravenously administered glycerol test is greatly useful method for detection of endolymphatic hydrops. Moreover, in view of the criterion it was strongly recommended at least 10dB inprovement in pure tone threshold at two or more frequencies as the significantly positive test.

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