喉頭白色病変の臨床的検討

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  • Clinicopathological Study of White Lesion of the Larynx.

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It has been pointed out by many clinicians that white lesion of the larynx should be treated carefully as a precancerous lesion. Clinically, it is called leukoplakia, hyperkeratosis and pachydermia. Histopathologically, it is varied with the appearance of cell atypia and cancer cell in addition to pathological keratosis. So, its clinical and histopathological concepts have not yet been established.<BR>Fifty-one cases were studied excluding those who were diagnosed as laryngeal cancer on the first histopathological examination among cases of white lesion of the larynx which were treated at this hospital during 12 years from December, 1977 to December, 1989. The 51 cases are broken down to 46 men (34-76 years of age, 56.4 years on the average) and 5 women (42-60 years of age, 49.8 years on the average).<BR>Six cases were intractable-recurrent. Dysplasia was noted in all the cases. Of them, 3 cases had high-grade dysplasia and 3 cases low-grade dysplasia. Three of the 51 cases were suspected of canceration, showing findings of dysplasia.<BR>From the findings above, it is concluded that the presence of dysplasia is the most important factor that affects the prognosis of white lesion of the larynx.

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