色素性母斑の２例と文献的考察

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  • Two cases of pigmented nevus with a review of the literature.

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Pigmented nevus is a proliferative hamartoma-like mole consisting of melanogenic cells. Compared with the incidence of pigmented nevus on the skin, its occurrence on the oral mucosa is rather rare. We experienced two pigmented nevus cases: a compound pigmented nevus on the gingiva of mandible (21-year-old female) and a junctional pigmented nevus on the palate (six-year-old female). We conducted immunohistochemical investigations in these cases and reported their results. Comparatively reviewing the reported cases in both Japanese and overseas literature, we obtained the following results.<BR>(a) Histologically, the intradermal type is the most common, compound and junctional types follow sequentially.<BR>(b) Intradermal and compound types usually develop on the gingiva of mandible, lip, and buccal mucosa. The junctional type often develops on the palate.<BR>(c) More women than men have pigmented nevi.<BR>(d) Pigmentation occurs in most cases.<BR>(e) Almost all intradermal and compound pigmented nevi are protuberant, whereas pigmented nevus of the junctional type is usually smooth.

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