クリプトコックス症に関する問題点

DOI 被引用文献1件
  • 伊藤 章
    横浜市立大学医学部第一内科学教室

書誌事項

タイトル別名
  • Certain Problems of Cryptococcosis

この論文をさがす

抄録

The reports on a total of 453 cases with deep-seated cryptococcosis were obtained from the medical, surgical, pediatric and urological departments of the university hospitals and the clinical services of the major national, public and private hospitals throughout the country by questionnairing conducted during the period from January 1971 through August 1981 (48.8% replied) as well as from the issues of “Igaku Chuo Zasshi” (Japan Centra Revuo Medicina) reported from 1971 through 1980 (the duplicated cases were omitted). These cases were classified by diagnosis, treatment, prognosis, etc. and certain problematic points were examined.<br>Cryptococcosis occurs in 30-60 cases annually. The ratio of male to female patients is 1.3:1 and people at the age of 20-69 years are most susceptible to this disease. In the reported cases, 252 cases had CNS cryptococcosis, 132 cases, pulmonary cryptococcosis, and 82 cases, systemic cryptococcosis, and the survival rate was 39.1% (177 cases), 49.1% (55 cases) and 2.4% (2 cases), respectively. On the basis of these figures, the following issues should be taken up for discussion:<br>1. It seems that in recent years the actual number of cases with cryptococcosis is increasing although the reported cases are decreasing.<br>2. It is desirable to spread serological diagnostic procedure for early diagnosis of the disease.<br>3. Cryptococcosis has become a noticeable disease as one of opprotunistic infections. The patients with the disease often have leukemia, malignant lymphoma or collagen disease as the underlying disease and a possible relationship between cryptococcosis and immunodeficiency will become an issue in the future.<br>4. Development of a more potent antimycotic agent with fewer side effects is desirable since any drug better than amphotericin B and 5-fluorocytosine is not available.

収録刊行物

被引用文献 (1)*注記

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ