Dual energy x-ray absorptiometryによるヒト下顎骨骨塩定量に関する研究

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  • Determination of bone mineral density in human mandible by dual energy x-ray absorptiometry.

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<p>Preliminary evaluation of the performance of dual energy x-ray absorptiometry (DEXA) demonstrated a number of benefits for application to the mandible: excellent accuracy, good replication, little effect on absootion by soft tissues and little influence of the distance between the bone and the scanning table. DEXA measurement of the bone mineral density (BMD) was undertaken in 211 normal volunteers (104 males and 107 females) and 48 hemodialysis patients (29 males and 19 females). The mandible, lumbar spine, femoral neck, greater trochanter and radius were the sites of measurements. In the normal volunteers, the patterns of BMD changes at five sites differed by age and sex. The BMD changes in the mandible differed by sex. BMD decreased almost consisitently during menopause in females. In males, BMD decreased slightly after 50 years of age. The BMD decrease by aging was the least in the mandible in both sexes, compared to the four other sites. This indicates the specific characteristic of the mandible. In the hemodialysis patients, BMD at the five sites showed different patterns of change in relation to age, sex and duration of hemodialysis and different patterns of BMD changes were demonstrated between the hemodialysis patients and the normal volunteers. At all the five sistes examined, the duration of hemodialysis seemed to have a stronger effect on BMD than aging. BMD measured at the five sites, BMD in the mandible was most closely correlated to the duration of hemodialysis.</p>

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