Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin.

DOI Web Site 被引用文献29件
  • D Höfer
    Institute of Anatomy, University of Würzburg, Germany.
  • B Püschel
    Institute of Anatomy, University of Würzburg, Germany.
  • D Drenckhahn
    Institute of Anatomy, University of Würzburg, Germany.

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<jats:p>The alpha-subunit of the trimeric G-protein complex specific for taste receptor cells of the tongue, alpha-gustducin, is described here to be also expressed in the stomach and intestine. The alpha-gustducin-containing cells were identified as brush cells that are scattered throughout the surface epithelium of the gut and share structural features of taste receptor cells of the tongue. These findings provide clues to the long-sought molecular and cellular basis for chemoreception in the gut.</jats:p>

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