Ca <sup>2+</sup> -Dependent Protein Kinases and Stress Signal Transduction in Plants

  • Jen Sheen
    Department of Genetics, Harvard Medical School, and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

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<jats:p> Stress responses in plants involve changes in the transcription of specific genes. The constitutively active mutants of two related Ca <jats:sup>2+</jats:sup> -dependent protein kinases (CDPK1 and CDPK1a) activate a stress-inducible promoter, bypassing stress signals. Six other plant protein kinases, including two distinct CDPKs, fail to mimic this stress signaling. The activation is abolished by a CDPK1 mutation in the kinase domain and diminished by a constitutively active protein phosphatase 2C that is capable of blocking responses to the stress hormone abscisic acid. A variety of functions are mediated by different CDPKs. CDPK1 and CDPK1a may be positive regulators controlling stress signal transduction in plants. </jats:p>

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  • Science

    Science 274 (5294), 1900-1902, 1996-12-13

    American Association for the Advancement of Science (AAAS)

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