慢性副鼻腔炎の細菌学的検討とマクロライド療法に関する治療効果

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  • A Bacteriological Investigation of Chronic Rhinosinusitis and Macrolide Treatment.

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In this study, nasal discharge specimens of patients suffering from chronic rhinosinusitis were examined for bacteria. Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrholis were the main types of bacteria that were isolated from the specimens. The patients were assigned to two groups according to age. The first group consisted of patients aged ten or younger, and the second group consisted of patients aged eleven or older. Haemophilus influenzae appeared more frequently in the first group, whereas Pseudomonas aeruginosa appeared more frequently in the second group (p<0.01, p<0.005). When the patients were divited into two groups according to the presence or absence of nasal polyps and asthma, we found that Pseudomonas aeruginosa appeared at a significantly higher frequency in the group with both nasal polyps and asthma than in the other group. Here, we discuss the efficacy of macrolide treatment, to which Pseudomonas aeruginosa are resistant, and present data on patients with nasal polyps who received macrolide treatment.

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