Metabolic pathways and physiological and pathological significances of lysolipid phosphate mediators
抄録
<jats:title>Abstract</jats:title><jats:p>Lysophosphatidic acid and sphingosine 1‐phosphate are structurally simple and physiologically very important lysophospholipids. Because they possess distinct structural backbones (glycerol and sphingosine, respectively), there are different metabolic pathways for their intracellular production. Recently, several key enzymes that produce or degrade these lysolipid phosphate mediators extracellularly have been characterized. This review focuses on the physiological and pathophysiological significances of the extracellular metabolic pathways involving recently characterized exo‐type lysophospholipase D, ecto‐type phospholipase A, and ecto‐type lipid phosphate phosphatase. © 2004 Wiley‐Liss, Inc.</jats:p>
収録刊行物
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- Journal of Cellular Biochemistry
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Journal of Cellular Biochemistry 92 (5), 869-881, 2004-06-28
Wiley
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詳細情報 詳細情報について
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- CRID
- 1363670319250172288
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- NII論文ID
- 80016808155
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- ISSN
- 10974644
- 07302312
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- データソース種別
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