The Genome of the Diatom <i>Thalassiosira Pseudonana</i> : Ecology, Evolution, and Metabolism

DOI Web Site 被引用文献77件
  • E. Virginia Armbrust
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • John A. Berges
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Chris Bowler
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Beverley R. Green
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Diego Martinez
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Nicholas H. Putnam
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Shiguo Zhou
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Andrew E. Allen
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Kirk E. Apt
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Michael Bechner
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Mark A. Brzezinski
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Balbir K. Chaal
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Anthony Chiovitti
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Aubrey K. Davis
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Mark S. Demarest
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • J. Chris Detter
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Tijana Glavina
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • David Goodstein
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Masood Z. Hadi
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Uffe Hellsten
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Mark Hildebrand
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Bethany D. Jenkins
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Jerzy Jurka
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Vladimir V. Kapitonov
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Nils Kröger
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Winnie W. Y. Lau
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Todd W. Lane
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Frank W. Larimer
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • J. Casey Lippmeier
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Susan Lucas
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Mónica Medina
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Anton Montsant
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Miroslav Obornik
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Micaela Schnitzler Parker
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Brian Palenik
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Gregory J. Pazour
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Paul M. Richardson
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Tatiana A. Rynearson
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Mak A. Saito
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • David C. Schwartz
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Kimberlee Thamatrakoln
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Klaus Valentin
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Assaf Vardi
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Frances P. Wilkerson
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.
  • Daniel S. Rokhsar
    School of Oceanography, University of Washington, Seattle, WA 98195, USA.

抄録

<jats:p> Diatoms are unicellular algae with plastids acquired by secondary endosymbiosis. They are responsible for ∼20% of global carbon fixation. We report the 34 million–base pair draft nuclear genome of the marine diatom <jats:italic>Thalassiosira pseudonana</jats:italic> and its 129 thousand–base pair plastid and 44 thousand–base pair mitochondrial genomes. Sequence and optical restriction mapping revealed 24 diploid nuclear chromosomes. We identified novel genes for silicic acid transport and formation of silica-based cell walls, high-affinity iron uptake, biosynthetic enzymes for several types of polyunsaturated fatty acids, use of a range of nitrogenous compounds, and a complete urea cycle, all attributes that allow diatoms to prosper in aquatic environments. </jats:p>

収録刊行物

  • Science

    Science 306 (5693), 79-86, 2004-10

    American Association for the Advancement of Science (AAAS)

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