Magnetosomes Are Cell Membrane Invaginations Organized by the Actin-Like Protein MamK

DOI Web Site 24 Citations
  • Arash Komeili
    Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA 91125, USA.
  • Zhuo Li
    Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA 91125, USA.
  • Dianne K. Newman
    Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA 91125, USA.
  • Grant J. Jensen
    Division of Geological and Planetary Sciences, California Institute of Technology, Pasadena, CA 91125, USA.

Abstract

<jats:p> Magnetosomes are membranous bacterial organelles sharing many features of eukaryotic organelles. Using electron cryotomography, we found that magnetosomes are invaginations of the cell membrane flanked by a network of cytoskeletal filaments. The filaments appeared to be composed of MamK, a homolog of the bacterial actin-like protein MreB, which formed filaments in vivo. In a <jats:italic>mamK</jats:italic> deletion strain, the magnetosome-associated cytoskeleton was absent and individual magnetosomes were no longer organized into chains. Thus, it seems that prokaryotes can use cytoskeletal filaments to position organelles within the cell. </jats:p>

Journal

  • Science

    Science 311 (5758), 242-245, 2006-01-13

    American Association for the Advancement of Science (AAAS)

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