Embolic infarction followed by serial bone SPECT and MR fusion images -the door to SPECT/MR-
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- Tsujikawa Tetsuya
- Department of Radiology, University of Fukui
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- Kamibayashi Tomohito
- Department of Radiology, University of Fukui
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- Tsuchida Tatsuro
- Department of Radiology, University of Fukui
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- Ohkoshi Yusuke
- Department of Radiology, University of Fukui
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- Kimura Hirohiko
- Department of Radiology, University of Fukui
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We recently experienced a case of cerebral infarction incidentally found by whole body bone scintigraphy for the detection of bone metastasis from renal cell carcinoma. Additional bone SPECT and brain MR fusion images clearly demonstrated the wedge-shaped uptake of tracer corresponded to the abnormal intensity reflecting subacute cerebral infarction. Follow-up bone scan and fused images with MRI showed complete resolution of the abnormal uptake in chronic phase. A breakdown in the normal blood-brain barrier results in abnormal ionic calcium flux into the cells following altered cell membrane integrity leading to precipitation of calcium salts which eventually binds to bone imaging tracer such as 99mTc-methylene diphosphonate. That is, increased accumulation of bone seeking agents represents lethal cell death. The recent development of software and hardware has enabled the fusion of functional and anatomic images. Image fusion between SPECT with various tracers and MRI is expected to provide clues as to the underlying cause of diseases and to decide our treatment planning in the near future. J. Med. Invest. 57: 334-337, August, 2010
収録刊行物
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- The Journal of Medical Investigation
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The Journal of Medical Investigation 57 (3,4), 334-337, 2010
国立大学法人 徳島大学医学部
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詳細情報 詳細情報について
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- CRID
- 1390001204243683584
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- NII論文ID
- 130004465226
- 80021262353
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- NII書誌ID
- AA11166929
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- ISSN
- 13496867
- 13431420
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- Crossref
- CiNii Articles
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