Successful Extracorporeal Life Support for Life-threatening Hypercapnia with Bronchiolitis Obliterans after Allogeneic Hematopoietic Stem Cell Transplantation

• Waseda Koichi

• Tanimoto Yasushi

• Ichiba Shingo

• Miyahara Nobuaki

• Murakami Toshi

• Ochi Nobuaki

• Terado Michihisa

• Nagano Osamu

• Maeda Yoshinobu

• Kanehiro Arihiko

• Ujike Yoshihito

• Tanimoto Mitsune

抄録

Bronchiolitis obliterans (BO) is a disease with a poor prognosis, and a key factor that limits long-term survival after allogeneic hematopoietic stem cell transplantation (HSCT). We here report a case of a 31-year woman with acute lymphatic leukemia, which was treated by chemotherapy and HSCT, and consequently developed BO 2 years after HSCT. A non-tuberculous mycobacterial infection occurred and showed gradual exacerbation. She started taking anti-mycobacterial drugs, but lost appetite, felt tired and finally lost consciousness one month after beginning medication. Arterial blood gas revealed marked hypercapnia. Using extracorporeal life support (ECLS), the carbon dioxide concentration was reduced and her consciousness recovered. To our knowledge, this is the first case in which ECLS was successfully used for hypercapnia in a patient with BO.

収録刊行物

• Acta Medica Okayama

  Acta Medica Okayama 65 (6), 403-406, 2011-12

  Okayama University Medical School

キーワード

• extracorporeal life support
• hypercapnia
• bronchiolitis obliterans
• noninvasive positive pressure ventilation

詳細情報

• CRID: 1390009224819598976
• NII論文ID: 80022180813
• NII書誌ID: AA00508441
• ISSN: 0386300X
• DOI: 10.18926/amo/47266
• PubMed: 22189481
• Web Site: https://ousar.lib.okayama-u.ac.jp/47266
• Web Site: https://search.jamas.or.jp/link/ui/2012323436
• 本文言語コード: en
• データソース種別:
  • JaLC
  • IRDB
  • PubMed
  • CiNii Articles