The Thyroid
著者
書誌事項
The Thyroid
（Current endocrinology）
Elsevier, c1987
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注記
Includes bibliographies and index
内容説明・目次
内容説明
This newest addition to the Current Endocrinology series, The Thyroid, is a complete guide to the management of thyroid diseases. The book covers all aspects of the thyroid and its diseases, including physiology of the gland and its hormones, autoimmune mechanisms, thyroid function tests, and the effects of illness on thyroid functions. The Thyroid also dedicates a chapter to each of the major categories of thyroid disease - hyperthyroidism, hypothyroidism, goiter, and thyroid neoplasia. This book promises to be a valuable reference for both primary care physicians and practicing endocrinologists who manage thyroid disease.
目次
Foreward. Preface. Contributors. Physiology of the Thyroid Gland and its Hormones (W.L. Green). Introduction: An overview of thyroid physiology. Development and anatomy. Hormone synthesis and secretion. Fate of thyroid hormones in peripheral tissues. Neuroendocrine regulation: TSH and TRH. Actions of the thyroid hormones. References. Autoimmune Mechanisms in Thyroid Disease (B. Rapoport). Introduction. Immunologic principles in autoimmunity. Etiology of autoimmune thyroid disease. Heredity of autoimmune thyroid disease. Humoral thyroid stimulators in Graves' disease. Cell-mediated immunity and lymphocytic function in Graves' disease. Immune complexes in autoimmune thyroid diseases. Ophthalmopathy in autoimmune thyroid disease. Pretibial myxedema. Experimental models for Grave's disease. Thyroid antibodies in Hashimoto's thyroiditis. Pathogenesis of Hashimoto's thyroiditis. References. Laboratory Evaluation of Thyroid Status (R.R. Cavalieri). Introduction. Thyroidal iodine metabolism. The perchlorate test for defective intrathyroidal organification. Tests of thyroid iodine turnover and release. Estimation of stable iodine in the thyroid. Measurement of circulating thyroid hormone. Measurement of total hormone concentration. Measurement of free hormone. Tests of the hypothalamic-pituitary-thyroid axis. Metabolic indices: tests of thyroid hormone action. Achilles reflex time. Physiologic and pathologic factors influencing circulating hormone. Applications of thyroid function tests to special problems. References. Hyperthyroidism (R.D. Utiger). Introduction. Pathophysiology. Causes of hyperthyroidism. Clinical manifestations of hyperthyroidism. Laboratory diagnosis of hyperthyroidism. Treatment of hyperthyroidism. Special situations. Extrathyroidal manifestations of Graves' disease. References. Hypothyroidism (C.H. Emerson, C. Liberman, and L.E. Braverman). Introduction. Etiology, incidence, and pathogenesis. Clinical features of hypothyroidism. Effects of primary hypothyroidism on function of other endocrine glands. Laboratory diagnosis of hypothyroidism. Treatment of hypothyroidism. References. Goiter (C. Liberman, C.H. Emerson, and L.E. Braveman). Introduction. Primary goiter. Secondary goiter. Summary. References. Thyroid Neoplasia (M.C. Gershengorn, and J. Robbins). Introduction. Classification and pathologic anatomy. Etiology. Incidence. Diagnosis. Preoperative management of nodular thyroid disease. Management of radiation-exposed patients. Clinical features, natural history, and management of thyroid carcinoma. Concluding remarks. References. Index.
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