Textbook of human genetics

著者

書誌事項

Textbook of human genetics

Max Levitan

Oxford University Press, 1988

3rd ed

大学図書館所蔵 件 / 全19件

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注記

Bibliography: p. [422]-433

Includes index

内容説明・目次

内容説明

Professor Max Levitan has thoroughly revised and updated this established textbook on human genetics, to incorporate the great changes in human genetics over the last decade. He reviews the basic laws of genetics, the common genetic diseases, and their causes in humans, drawing upon numerous examples from human biology and medicine. He presents the latest data and techniques, including the molecular recognition of gene expression in humans, and the use of restriction fragment length polymorphisms (RFLPs) to map human genes and identify genetic diseases. New chapters have been added on human immunogenetics, oncogenes, and cancer. The author explains complex concepts with clarity, and uses an extensive array of diagrams and illustrations, including electron micrographs and clinical photographs of all common genetic disorders. Advanced undergraduates and graduate students in human genetics; biology students who have had an introductory course in Mendellian genetics; medical students interested in human genetics.

目次

  • Simple Mendelian inheritance
  • Human chromosomes
  • Disorders of chromosome number
  • Disorders of chromosome structure
  • Gene structure, gene action, and the phenotype
  • The molecular biology of human genes
  • Sex-related inheritance
  • Chance and the distribution of families
  • The random mating law
  • Relationship and consanguinity
  • Factors causing changes in gene frequencies
  • Independent genes
  • Linked genes
  • Epistatic and regulatory interactions
  • Polygenic inheritance
  • Immunogenetics
  • Neoplastic disease and oncogenes
  • Genetic counselling: prenatal diagnosis and empiric risk.

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