Understanding cell toxicology : principles and practice

書誌事項

Understanding cell toxicology : principles and practice

Erik Walum, Kjell Stenberg, D. Jenssen

(Ellis Horwood series in biochemistry and biotechnology)

E. Horwood, 1990

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注記

Includes bibliographical references (p. 180-201)

内容説明・目次

内容説明

This study introduces the use of cells cultured in vitro for the analysis of drug toxicity, as well as cell structure as the end-point for toxicity, membrane permeability changes, cell proliferation and cell metabolism. A summary of in vitro toxicity testing is included in the text.

目次

  • Why cell toxicology
  • the cell
  • how to culture cells
  • toxokinetics in cell culture
  • cell structure toxicity
  • cell metabolism toxicity
  • cell genotoxicity
  • oncogenicity
  • validation and predictivity.

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