Biomedical applications of mass spectrometry
Author(s)
Bibliographic Information
Biomedical applications of mass spectrometry
(Methods of biochemical analysis / edited by David Glick, v. 34)
Wiley, c1990
Available at / 46 libraries
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Library & Science Information Center, Osaka Prefecture University
NDC6:491.4||G2||3410091677195
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National Institutes of Natural Sciences Okazaki Library and Information Center図
464/Me/349215980211
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Note
Includes bibliographical references and indexes
Description and Table of Contents
Description
The purpose of this book is to give the reader, both the novice and the authority, a presentation of the application of mass spectrometry to a variety of biological problems. It begins by giving an overview of mass spectrometry, including a review of some of the recent advances that make this field of analytical biochemistry so exciting. Each subsequent chapter is prepared by an authority in the field. The chapters are not a compilation of methods but, rather, they provide insight into approaches that mass spectroscopists have used to solve these problems. Each chapter provides guidance in using appropriate methods for isolation and purification of the compound class prior to analysis or characterization by mass spectrometry. It also provides a tutorial on mass spectral interpretation based on the fragmentation pathways usually encountered for the particular compound type. In many cases, chemical modification of the parent compound and corresponding mass shifts in the spectrum are co-ordinated through reaction schemes and didactic descriptions.
Modern approaches to analysis based on fast-atom bombardment are described in conjunction with the more conventional analysis by electron impact and chemical- ionization mass spectrometry.
Table of Contents
- Mass Spectrometry: An Introduction
- Mass Spectrometry of Carbohydrates
- Peptide Sequencing by Mass Spectrometry
- Mass Spectrometry of Nucleic Acid Components
- Mass Spectrometry in Pharmacology.
by "Nielsen BookData"