Portal hypertension : clinical and physiological aspect

書誌事項

Portal hypertension : clinical and physiological aspect

Kunio Okuda, Jean-Pierre Benhamou (eds.)

Springer-Verlag, c1991

  • : ja
  • : gw
  • : us

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注記

Includes bibliographical and index

内容説明・目次

巻冊次

: gw ISBN 9783540700548

内容説明

This reference work describes both the basic aspects and clinical features of portal hypertension, an abnormal physiological state that can lead to serious complications with fatal consequences. The authors examine the physiology of portal hypertension, its histological basis and various causes. The changes in portal haemodynamics and the methods for investigating such changes are thoroughly discussed. The various portal-systemic collateral routes and the diagnosis of portal hypertension and collaterals are shown. Clinical manifestations, endoscopy for esophageal varices, complications (particularly bleeding varices) and their management are critically evaluated.
巻冊次

: ja ISBN 9784431700548

内容説明

Portal hypertension is the abnormal pathophysiologic state that develops in liver cirrhosis and certain other disorders with characteristic clinical and hemodynamic features. There has been great progress in our under- standing and management of portal hypertension, particularly in the diagnostic and therapeutic approaches. The so-called Banti's syndrome, a disorder whose existence had long been questioned, is now a well-defined portal hypertensive disease. The recently introduced Doppler ftowmetry is currently yielding new information on portal hemodynamics. Endoscopic sclerotherapy and beta-blockers have come to be widely used in the man- agement and prevention of variceal bleeding. In spite of all these advances, a number of unsolved questions remain, such as whether sclerotherapy, pharmacotherapy or surgery is warranted for prevention of bleeding, which is more effective as an elective treatment, the surgical or endoscopic approach, and whether surgical portacaval shunt should be totally replaced by selective shunt operations. These new developments and problems are clearly and comprehensively described and discussed by the foremost authorities in 44 chapters, which are divided into five sections: 1) Patho- physiology, 2) Hemodynamic Investigations, 3) Imaging Investigations, 4) Clinical and Pathological Features, and 5) Esophageal and Gastrointestinal Bleeding. The primary goal of this monograph, to provide a framework of patho- physiology of portal hypertension with authoritative descriptions of the clinical and laboratory manifestations of various portal hypertensive dis- orders, has clearly been achieved by these excellent contributions.

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