Infectious diseases of humans : dynamics and control

著者

書誌事項

Infectious diseases of humans : dynamics and control

Roy M. Anderson and Robert M. May

Oxford University Press, 1991

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注記

Includes bibliographical references

Includes indexes

内容説明・目次

内容説明

This book combines mathematical models with extensive use of epidemiological and other data to achieve a better understanding of the overall dynamics of populations of pathogens or parasites and their human hosts. The authors thus provide an analytic framework for evaluating public health strategies aimed at controlling or eradicating particular infections. With rising concern for programmes of primary health care against such diseases as measles, malaria, river blindness, sleeping sickness, and schistosomiasis in developing countries, and the advent of HIV/AIDS and other "emerging viruses", such a framework is increasingly important. Throughout, the mathematics is used as a tool no more and no less for thinking clearly about fundamental and applied problems having to do with infectious diseases. The book is divided into two major parts, one dealing with microparasites (viruses, bacteria, and protozoans) and the other with macroparasites (helminths and parasitic arthropods). Each part begins with simple models, developed in a biologically intuitive way, and then goes on to develop more complicated and realistic models as tools for public health planning. This book synthesizes previous work in this rapidly growing area with a good deal of new material.

目次

  • Part 1 Microparasites: biology of host-microparasite associations
  • the basic model - statics
  • static aspects of eradication and control
  • the basic model - dynamics
  • dynamic aspects of eradication and control
  • beyond the basic model - empirical evidence of inhomogeneous mixing
  • age-related transmission rates
  • genetic heterogeneity
  • social heterogeneity and sexually transmitted diseases
  • spatial and other kinds of heterogeneity
  • endemic infections in developing countries
  • indirectly transmitted microparasites. Part 2 Macroparasites: biology of host-macroparasite associations
  • the basic model - statics
  • the basic model - dynamics
  • acquired immunity
  • heterogeneity within the human community
  • indirectly transmitted helminths
  • experimental epidemiology
  • parasites, genetic variability, and drug resistance
  • the ecology and genetics of host-parasite associations.

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