Interleukin 8 (NAP-1) and related chemotactic cytokines

著者

書誌事項

Interleukin 8 (NAP-1) and related chemotactic cytokines

volume editor, M. Baggiolini, C. Sorg

(Cytokines, vol. 4)

Karger, 1991

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Interleukin-8 (IL-8) is a peptide with chemotactic and activating effects on neutrophils. It is recognized today as the prototype of a new class of chemotactic cytokines which are gaining increasing attention as tissue-derived inflammatory mediators. Four years after the identification of IL-8, this book presents an overview of the biochemical, molecular biological and pathophysiological properties of this new class of inflammatory proteins. Written by leading researchers, this collection of essays can not only be used as a reference source for those already active in the field, but also provides detailed information for newcomers interesed in chemotactic cytokines and their implication in inflammation and host defence.

目次

  • Neutrophil activation and the effects of interleukin-8/neutrophil-activating peptide 1, M. Baggiolini et al
  • NMR and X-ray analysis of the three dimensional structure of interleukin-8, G.M. Clore et al
  • regulation of IL-8 production and the characteristics of the receptors for IL-8, N. Mukaida and K. Matsushima
  • generation of NAP-1 and related peptides in psoriasis and other inflammatory skin diseases, J.M. Schroder
  • generation and properties of neutrophil-activating peptide 2, A. Walz
  • structural, regulatory and functional studies of the GRO gene and protein, R. Sager et al
  • macrophage inflammatory proteins 1 and 2 - an overview, B. Sherry et al
  • monocyte chemoattractant protein-1 - structure and function, T. Yoshimura and E.J. Leonard.

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