Cystic fibrosis, basic and clinical research : proceedings of the 17th Annual Meeting of the European Working Group for Cystic Fibrosis, Copenhagen, 17-21 June 1991
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書誌事項
Cystic fibrosis, basic and clinical research : proceedings of the 17th Annual Meeting of the European Working Group for Cystic Fibrosis, Copenhagen, 17-21 June 1991
（International congress series, no. 977）
Excerpta Medica, 1992
- alk.paper
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The past 30 years have witnessed a dramatic improvement in life expectancy and quality of life for patients with cystic fibrosis. As a consequence, cystic fibrosis is no longer a paediatric disease. In Western Europe and North America 20% of patients are adults. Some adult cystic fibrosis patients have graduated from universities, some have jobs, some are married, and have children. Consequently, the spectrum of symptoms and complications of the basic disease changes. It is important that clinicians recognize the specifically adult related problems and that this knowledge is conveyed to their colleagues. At the same time, the progress of basic science such as genetics, physiology of membranes and immunology have rapidly progressed, all making an impact towards the best possible care for patients. These Proceedings of the 17th Working Group for Cystic Fibrosis provide a wealth of new information in the basic science and clinical treatment of cystic fibrosis. Chapters written by internationally established scientists are provided, which should prove to be of value for paediatricians, chest physicians, microbiologists, and scientists working with cystic fibrosis patients.
目次
Screening and prenatal diagnosis Screening and prenatal diagnosis of cystic fibrosis (J.E. Dankert-Roelse). CF cell cultures Role of CFTR in salivary secretion (M.A. McPherson, et al.). The culture of human epithelial cell lines for the study of cystic fibrosis (C.M. Lee). Model systems-sweat glands (P.S. Pedersen). Regulation of the chloride conductance of colonic carcinoma cells (K. Kunzelman, et al.). Metabolism and hyperalimentation Metabolism and hyperalimentation in cystic fibrosis: An overview (J.A. Dodge, A. O'Rawe). Can we improve airway clearance? Can we improve airway clearance? (M.S. Zach). Virulence factors of Pseudomonas aeruginosa The regulation of alginate biosynthesis by mucoid Pseudomonas aeruginosa (N.J. Russell, P.J. Tatnell, P. Gacesa). The multifactorial virulence of Pseudomonas aeruginosa (G. Doring). Role of Pseudomonas aeruginosa lipopolysaccharide and tumor necrosis factor in cystic fibrosis (A. Fomsgaard, N. Hoiby). Extracellular lipase of Pseudomonas aeruginosa : Biochemistry and potential role as a virulence factor (K.-E. Jaeger, D.A. Kinscher, B. Konig, W. Konig). Pore-forming Pseudomonas aeruginosa cytotoxin as a pathogenic factor (F. Lutz, et al.). Prevention and early treatment of Pseudomonas aeruginosa infection Prevention and early treatment of Pseudomonas aeruginosa infection (S.S. Pedersen, C. Koch, N. Hoiby). Treatment of chronic Pseudomonas aeruginosa infection: Effect and side-effects of antibiotics Treatment of chronic Pseudomonas aeruginosa infection in cystic fibrosis: Effects and side-effects of antibiotics (C. Koch, S.S. Pedersen, N. Hoiby). Immunology and vaccines Phase I clinical evaluation of a Pseudomonas aeruginosa alginate-toxin A conjugate vaccine (S.J. Cryz Jr, B. Althaus, J.U. Que). Safety and immunogenicity of an octavalent Pseudomonas aeruginosa O-polysaccharide-toxin A conjugate vaccine in cystic fibrosis patients (U.B. Schaad, et al.). Lung inflammation and anti-inflammatory treatment Lung inflammation and anti-inflammatory treatment (S. Suter). Organ transplantation for CF patients Lung transplantation for cystic fibrosis (M.E. Hodson). Psychosocial aspects The psychosocial situation of independently living CF adults (S. Perobelli). Quality of life after heart-lung transplantation (HLT) (F. Duncan- Skingle). Index of authors.
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