Mechanoreception by the vascular wall

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Bibliographic Information

Mechanoreception by the vascular wall

edited by Gabor M. Rubanyi

Futura, c1993

Available at  / 8 libraries

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Includes bibliographical references and index

Description and Table of Contents

Description

With contributions from leading experts, this book provides an in-depth review of the state-of-the-art of current knowledge on the biophysical principles of mechanoreception, and the phenomenon of myogenic tone and autoregulation. The controversial and fascinating new developments of the involvement of the endothelium in the mechanosensing function of blood vessels, including spontaneous vasomotion, are covered. Another chapter gives an overview of the role of mechanical forces in angiogenesis.

Table of Contents

  • Biophysics of mechanotransduction
  • Stretch-dependent myogenic tone in isolated blood vessels
  • The myogenic response in microvascular networks
  • The role of the myogenic response in autoregulation of blood flow
  • Endothelial modulation of pressure-dependent myogenic vasoconstruction
  • Pressure-induced vasoconstriction in isolated canine carotid areteries is mediated by suppression of EDRF release
  • Pressure-induced vasoconstriction and membrane depolarisation is mediated by a diffusible endothelium-derived contracting factor in cat middle cerebral arteries
  • Cytochrome P450 metabolites of arachidonic acid in the control of vascular tone
  • Role of endothelium-derived nitric oxide in vasomotion
  • Physical forces and angiogenesis.

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