Bacterial endotoxin : recognition and effector mechanisms : proceedings of the 2nd Congress of the International Endotoxin Society, Vienna, 17-20 August 1992

書誌事項

Bacterial endotoxin : recognition and effector mechanisms : proceedings of the 2nd Congress of the International Endotoxin Society, Vienna, 17-20 August 1992

editors, Jack Levin ... [et al.]

(International congress series, no. 1020)(Endotoxin research series, v. 2)

Excerpta Medica, 1993

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注記

Includes index

内容説明・目次

内容説明

The field of endotoxin research is constantly expanding. Modern technology and tools are now providing so much data that the importance of identifying the data which are physiologically relevant and which will lead to the effective treatment of the wide variety of clinical disorders in which endotoxin may play an important role has assumed even greater significance than before. This book, the second volume in the Endotoxin Research series, presents all the papers formally presented at the above mentioned symposium, along with summaries of each session and important questions posed during the discussion periods.

目次

  • Opening remarks
  • Alois Nowotny 1922-1992
  • in memoriam - Professor J. Yuzuru Homma, MD (1919-1991)
  • introduction to Professor Otto Westphal's opening address
  • an old-timer's reflections on endotoxin. Part 1 LPS and lipid A biosynthesis, structure and conformation: the enzymatic synthesis of lipid A, C.R.H. Raetz
  • crystallization and molecular structure of escherichia coli Re and K-12 lipopolysaccharides, N. Kato et al
  • modelling the three-dimensional structure of lipopolysaccharide, M. Kastowsky
  • session summary, S. Kusumoto and P. Kosma. Part 2 Role of endotoxin in bacterial infection: genetics and the study of the virulence properties of haemophilus influenza lipopolysaccharide, D.J. Maskell and E.R. Moxon
  • molecular mimicry and host-modification of lipo-oligosaccharides, R.E. Mandrell
  • bactericidal and endotoxin-neutralizing activities of the bactericidal/permeability-increasing protein and its bioactive N-terminal fragment, J. Weiss et al
  • antibacterial and antiendotoxic actions and interactions of lipopolysaccharide antibodies and complement, M. Pollack et al
  • persistence of LPS in cells and tissues - role of LPS recognition in reaction arthritis, K. Granfors
  • session summary, P.H. Makela and L. Hinshaw. Part 3 Interactions of endotoxin with animal cells: LPS binding proteins, LPS and CD14 mediated activation of myeloid cells, P.S. Tobias et al
  • novel plasma proteins that mediate the interaction of LPS with CD14, S.D. Wright
  • interrelationship of LPS, pertussis toxin and the p73 LPS receptor on lymphoreticular cells, M.-G. Lei and C.D. Morrison
  • the 70kDa peptidoglycan/lipopolysaccharide receptor, R. Dziarski
  • CD14 - myeloid cell surface receptor involved in bacterial lipopolysaccharide recognition, V. Bail et al
  • lipid A binding proteins in 70Z/3 cells, T.N. Kirkland and P.S. Tobias
  • intracellular LPS-binding proteins and peptides found in limulus hemocytes, S. Iwanaga et al
  • session summary (part 1), R.J. Ulevitch
  • interferon-gamma, a mediator of infection-induced sensitization towards endotoxin, A. Freudenberg et a
  • introduction to the 70Z/3 model system, C.H. Sibley
  • the regulation of TNF production and endotoxin mitogenicity by lipoxygenases, F.U. Schade et al
  • the purine analog, 2-methylthio-ATP(2-MeS-ATP), protects mice from endotoxic death, P.J. Berties et al
  • LPS mimetic effects of taxol in LPS-inducible gene expression, glucocorticoid receptor expression and tyrosine phosphorylation in murine macrophages, S.N. Vogel et al. Part 4 Prevention and therapy of endotoxicosis - new approaches.

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