The Physics of heart and circulation

書誌事項

The Physics of heart and circulation

edited by Jan Strackee and Nico Westerhof

(Medical science series)

Institute of Physics Pub., 1993

大学図書館所蔵 件 / 5

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This book is aimed at those working on the physical aspects of heart and circulation. However, the book has a much wider scope: it also presents the physical and mathematical basis for the study of biological systems, not only as a way of thinking but also presenting basic information on all aspects of the cardiovascular system, such as fluid dynamics, elasticity, potential theory, mathematical modelling, etc. The book is of interest to graduate students and researchers in biomedical engineering, medical physics and the clinical sciences.

目次

  • The Heart in our Body. Historical Notes
  • Cardiovascular control
  • References. Basic Aspects of Cardiac Electrical Activity: Introduction
  • Principles of Membrane Excitability
  • composition of the Intra- and Extracellular Fluid
  • IOn Activity
  • The Membrane Potential
  • Ionic Pumps and Exchangers
  • The Excitable Membrane
  • Membrane Currents in Heart Cells
  • References. Electrocardiography: Introduction
  • Volume Conduction
  • Source Models
  • Volume Conductor Models
  • The Forward Problem
  • Inverse Procedures
  • Lead Systems
  • Body-surface Mapping
  • References. Cardiac Arhythmias: Introduction
  • Role of the Electrocardiogram (ECG)
  • Electrophysiological Mechanisms
  • Ventricular Tachycardia and fibrillation
  • Modelling Cardiac Arrhythmias
  • References. Rythms and Analysis Techniques: Neural Control of Arterial Pressure and heart Rate by the Baroreflex
  • Some Principles of Control Systems
  • Cardiovascular Signals: ECG and Arterial Blood Pressure
  • Oscillatory Phenomena in Heart rate and Blood Pressure: Some Tentative Explanations
  • Concluding Remarks
  • References. Contraction Mechanism in Striated Muscle: Introduction
  • Anatomy and Function
  • Sliding-filament Mechanism
  • Activation Process
  • Dynamic Properties of Contraction
  • References. Mechanics of the Wall of the Left Ventricle: Introduction
  • Models of the Mechanics of the Left Ventricle
  • Mechanisms to even Mechanical load in the Heart
  • Simplified Models of Left Ventricular Mechanics
  • Remodelling Mechanism of the Left Ventricle
  • Conclusion
  • References. Measurement of Systolic Ventricular Performance: Introduction
  • Assessing Ventricular performance
  • Pressure-volume Relations and Elastance
  • Measurement of Ventricular Volume
  • Conclusion
  • References. Relaxation and Diastole: Relaxation
  • Diastole
  • References. Cardiac Pump Function: Introduction
  • The Heart as a Pump
  • Power and Efficiency
  • The Heart and Arterial Systems
  • References. System Modelling of Ventricular Function: System Models of the Circulation
  • Ventricular Elastance
  • Ventricular 'Quick' Elastance
  • Ventricular Resistance
  • Quantitative Analysis of the three-component Model
  • the Deactivating Effect of Decreasing Flow
  • Identification of Ventricular constant-flow Ejection Parameters
  • Discussion and Conclusion
  • References. Biological Control: A System Analysis Approach: Man-made versus biological Systems
  • A Simple Feedback Loop
  • Interaction of Glands as an Example of a Biological Control System
  • The Central heating
  • Control of Coronary Blood flow
  • References. Elasticity of Tissues: Introduction
  • Definition of Mechanical Properties
  • Homogeneity and isotropy of Materials
  • Mechanical Properties of Sheets of Material
  • Mechanical Properties of Cylindrical Structures
  • Viscoelastic Models: Voigt and Maxwell Model
  • References. Viscosity of Media: Introduction
  • Stress Analysis
  • Strain
  • Constitutive Equations
  • Viscosity of Blood
  • Theoretical Bases of Viscosity Equations
  • Viscosity Measurements
  • Concluding Remarks
  • References. Velocity Profiles in Large Arteries: Navier-Stokes Equations
  • Dimensionless Numbers
  • Factors Influencing the Velocity Profile
  • Arterial and Valvular Flow Dynamics
  • References. Atherosclerosis and Blood Flow: Introduction
  • Characteristics of the Vessel Wall
  • Atherosclerotic Lesions
  • Theories for Atherosclerosis
  • Metabolic Hypotheses
  • Haemodynamic Hypotheses
  • Concluding Remarks
  • References. Diastolic flow in the Left Ventricle: Introduction
  • Methods
  • Clinical use of Doppler Ultrasound
  • Models of flow Patterns: Derivation, Calculation and Experiments
  • References. Arterial Haemodynamics: Introduction
  • Relation Between the Oscillatory Pressure Drop and Flow in a Tube
  • Input Impedance
  • Arterial Function
  • References. Physics of the Microcirculation: Introduction
  • Structure and Function of the Microcirculation
  • Blood Cells
  • Pressure Distribution in Microvessels
  • Arteriolar Diameter and Vascular Resistance
  • Methods to Change Transmural pressure non-invasively
  • Wall Tension
  • Blood Flow in a Microvascular Network Model
  • Microvessel Blood flow
  • Velocity Profiles in Microvessels
  • Apparent Viscosity
  • F^Doahraeus Effect: part 1
  • References. Isolated vessels: Introduction
  • Methodology
  • Mechanical properties of isolated vessels
  • Effect of drugs
  • Mechanical stimuli
  • References. Oxygen Supply and Exchange in the Myocardium: Introduction
  • Oxygen Diffusion
  • Oxygen Diffusion from Capillaries
  • Oxygen Diffusion and Blood Flow in a Single Capillary
  • Oxygen in a Capillary Network with Flow Heterogeneity
  • Haematocrit in the Microcirculation
  • The F^Doahraeus Effect: part 2
  • Acknowledgement
  • References. Central Venous Pressure and Control of Cardiac Output: Introduction
  • Heart-Lung Preparatio
  • The Systemic Circulation
  • Closure of Loop
  • Discussion of the Factors Involved in Determining Cardiac Output
  • References. The Effect of Cardiac Contraction on Coronary Flow: Introduction
  • Coronary Flow Impediment in Systole
  • Intramyocardial Pressure
  • References. Author Addresses. Author Index. Glossary. Subject Index.

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