Bibliographic Information

Nicotine and related alkaloids : absorption, distribution, metabolism, and excretion

edited by J.W. Gorrod and J. Wahren

Chapman & Hall, 1993

1st ed

Available at  / 3 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This book serves as a reference volume for anyone interested in nicotine and tobacco. An international team of authors contribute to this comprehensive review of current knowledge on the pharmacokinetics and metabolism of nicotine. A broad range of material on the action and uptake of nicotine and the consequences of exposure to it has been drawn together for the first time in this volume. This book should be of interest to research scientists and health professionals in pharmacology, toxicology and neurosciences.

Table of Contents

  • Biosynthesis and metabolism of nicotine and related alkaloids, Lowell Bush et al
  • the metabolism of nicotine in mammals - an overview, J.W. Gorrod
  • the role of cytochrome P450 in nicotine metabolism, H. Nakayama et al
  • nicotine metabolism beyond cotinine, G.B. Neurath
  • n-oxidation, n-demethylation and n-conjugation reactions of nicotine, P.A. Crooks
  • extrapatic metabolism of nicotine and related compounds, K. Vahakangas and O. Pelkonen
  • the metabolic fate of the minor tobacco alkaloids, Castagnoli Jr, N.
  • nicotine and metabolites - analysis and levels in body fluids, M. Curvall and E. Kazemi Vala
  • kinetics of nicotine and its metabolites in animals, J. Gabrielson and M. Gumbleton
  • pharmacokinetics of (s)-nicotine and metabolites in humans, P. Jacobs and N.L. Benowitz
  • sources of individual variation in nicotine pharmacokinetics, S. Cholerton et al
  • physiologically-based pharmacokinetics of nicotine, S.L. Schwartz et al
  • new methods for probing the in vivo disposition of nicotine in humans, J. Wahren.

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