Vascular growth factors and angiogenesis
著者
書誌事項
Vascular growth factors and angiogenesis
(Current topics in microbiology and immunology, 237)
Springer-Verlag, c1999
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This volume focuses on a family of growth factors and their receptors known as vascular endothelial growth factor (VEGFs). VEGFs are critical for endothelial cell function, both during physiological and pathological conditions. Thus, tumours depend on VEGF in order to promote ingrowth of blood vessels. Without VEGF, blood vessels will not form. There is a growing awareness that deregulated production or action of VEGF is initiating a large number of diseases. This book is written by scientists in the field for an audience with medical or life science background. The contributors present an overview of knowledge in the area of VEGF receptor structure and function in a series of reviews spanning from molecular signal transduction and cellular biology to the clinic.
目次
- Vascular endothelial growth factor - molecular and biological aspects
- structure, expression and receptor binding properties of PIGF
- structure, expression and receptor binding properties of novel vascular endothelial growth factors
- structure and function of vascular endothelial growth factor receptor 1 and 2
- vascular endothelial growth factor receptor 3
- vascular permeability factor/vascular endothelial growth factor and the significance of microvascular hyperpermeability in angiogenesis
- the angiopoetins - Yin and Yang in angiogenesis.
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