Challenges in rheumatoid arthritis
著者
書誌事項
Challenges in rheumatoid arthritis
Blackwell Science, c1999
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Bringing together the expertise of an international group of contributors the editors set out to address the most contentious issues posed by the problem of rheumatoid arthritis. The result is a series of state-of-the-art review papers on the subject which will interest all rheumatologists wishing to keep abreast of this fast moving field. "I believe that this book hopes to address some of the problems arising from the compartmentalisation of modern medicine." "Professor Bird is highly competent with an excellent reputation for balance and fair mindedness." "I suspect the target audience should be trainees in internal medicine who are considering rheumatology, or trainee rheumatologists in their early years. It could also be useful for those longer in the tooth who may feel they need a review of the area." "Since opinions are likely to present in abundance in such a book, and I have already suggested that it should be designed for a relatively short life, then topicality is the order of the day." Dr Michael L Snaith, Senior Lecturer in Rheumatology, University of Sheffield.
目次
- Pathogenesis of Rheumatoid disease: 1 Is rheumatic factor relevant? 2 Is apoptosis relevant? 3 Do cytokines have direct involvement in Pathogenesis? 4 Is it a T cell or a B cell disease? 5 Is enzymatic Chondrolysis specific? Disease Progression and Management: 1 Are measures of outcome helpful indicators? 2 The case for early aggressive therapy
- 3 The case for conservative therapy
- 4 Does histology or arthroscopy predict outcome? 5 How valuable is imaging? Drug Treatment: 1 Do early systemic steroids prevent disease? 2 Are intra-articular steroids as effective as systemic? 3 Should disease-modifying drugs be used alone or in combination? 4 Does immunotherapy have a role? 5 Is stem cell transplantation ethical and of value? 6 Will there be a role for gene therapy? Benefits and Risks: 1 Do prosthese last longer? Should joints be replaced earlier? 2 Are Occupational therapy and Physiotherapy cost-effective? 3 Is rheumatoid arthritis becoming a milder disease? 4 Should limited funds go to patient care or to research?.
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