Brain tumor invasion : biological, clinical, and therapeutic considerations

著者

    • Mikkelsen, Tom

書誌事項

Brain tumor invasion : biological, clinical, and therapeutic considerations

edited by Tom Mikkelsen ... [et al.]

Wiley-Liss, 1998

  • : cloth : alk. paper

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注記

"A John Wiley & Sons, Inc. publication."

Includes bibliographical references and index

内容説明・目次

内容説明

This book provides a comprehensive review of the biological mechanisms, including chemical carcinogenesis, growth factors, oncogenes, and tumor suppressers, responsible for the increased ability of gliomas to metastasize in the central nervous system. This book describes how these factors relate to the invasive process and how this information may be used in new anti-invasive therapeutic strategies.

目次

  • DEVELOPMENTAL BIOLOGY AND MOLECULAR NEURO--ONCOLOGY.
  • Cell Adhesion Molecules in the Migration of Neural Crest Cells (L. Larsen & K. Edvardsen).
  • Multiple Mechanisms of Neuronal Movement (P. Liesi).
  • Oncogenesis in the Nervous System (A. Aguzzi).
  • Growth Factors and Oncogenes in Neuro--Oncogenesis (B. Westermark & M. Nister).
  • Oncogenesis and Progression in Human Gliomas (V. Collins).
  • PATHOLOGICAL AND CLINICAL FEATURES OF MALIGNANT BRAIN TUMORS.
  • Malignant Gliomas: Histological Features, Invasion, and Relation to Clinical Symptons (S. Mork & K. Wester).
  • Brain Tumors That Disseminate Along Cerebrospinal Fluid Pathways and Beyond (M. Murakami, et al.).
  • Patterns of Spread and Recurrence of Glioma: Studies by Neuroimaging (S. Enam, et al.).
  • Proliferative Properties of Malignant Brain Tumors (D. Schiffer, et al.).
  • Meningiomas: Behavior in Vivo and in Vitro (L. de Ridder).
  • MODELS FOR THE STUDY OF BRAIN TUMOR INVASION IN VIVO AND IN VITRO.
  • In Vitro Invasion Through Basement Membrane Matrigel (S.--Y.
  • Song, et al.).
  • Glioma Cell Invasion Studied in Organotypic Coculture Models (P.--H.
  • Pedersen, et al.).
  • Experimental Animal Models for the Study of Brain Tumors (R. Chopra & T. Mikkelsen).
  • Local Spread and Satellitosis of Astrocytoma Cells (J. Bernstein & W. Goldberg).
  • The Growth of lacZ--Transfected Glioma Cells in the Central Nervous System (T. Read, et al.).
  • MECHANISMS OF INVASION.
  • The Role of Proteolytic Enzymes in Brain Tumor Infiltration (B. Frosch & B. Sloane).
  • Brain Extracellular Matrix, Adhesion Molecules, and Glioma Invasion (W. Paulus).
  • The Role of Growth Factors and Oncogenes in Tumor Cell Invasion (O. Laerum).
  • Autotaxin, Autocrine Motility Factor (M. Stracke, et al.).
  • Brain Invasion, Trophic Factors, and Central Nervous System Metastasis (G. Nicolson).
  • Cell Spread in the Central Nervous System: Anatomical Considerations (P. Enger, et al.).
  • NEW THERAPEUTIC STRATEGIES.
  • Anti--Invasive Brain Tumor Therapy: General Aspects and Future Strategies (M. Mareel, et al.).
  • Invasion and Angiogenesis: Translational Therapeutic Targets (R. Alessandro, et al.).
  • Gene Therapy and Brain Tumors (S. Yla--Herttuala).
  • GENERAL CONCLUSIONS AND FUTURE PROSPECTS.
  • Brain Tumor Cell Invasion: Present Knowledge and Future Prospects (O. Laerum & M. Rosenblum).
  • Index.

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