Advances in brain research : cerebrovascular disorders and neurodegeneration : proceedings of the 6th Hirosaki International Forum of Medical Science, held in Hirosaki, Japan, between 15 and 16 October 2002
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書誌事項
Advances in brain research : cerebrovascular disorders and neurodegeneration : proceedings of the 6th Hirosaki International Forum of Medical Science, held in Hirosaki, Japan, between 15 and 16 October 2002
（International congress series, 1251）
Excerpta Medica, 2003
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注記
Includes index
内容説明・目次
内容説明
This volume is the outcome of the 6th Hirosaki international Forum that was aimed to update the recent studies on neurological disorders of mainly elderly patients, particularly vascular and neurodegenerative disorders. Specific topics include genetic background of cerebrovascular diseases. Recent advance in the study of vascular spasm after subarachnoid hemorrhage is another major subject. In the field of neurodegenerative disorders, special emphasis was laid on the therapeutic strategy of Parkinson's disease. Pathogenesis of other degenerative diseases such as Alzheimer's disease is also a highlight of this volume.
目次
Chairman's address. I. Cerebrovascular disorders. New frontiers in cerebral vasospasm: signaling pathways (J.H.Zhang, H. Kimura, A. Nanda). A genome-wide linkage and a haploptype association studies mapped intracranial aneurysm to elastin locus on chromisome 7 (I. Inoue et al.). Changes in cerebral circulation and neuronal metabolism during chronic cerebral vasospasm after sub-arachnoid hemorrhage (Y. Handa et al.). Microcirculatory changes during acute phase of aneurysmal sub-arachnoid hemorrhage evaluated by clinical and experimental studies (H.Ohkuma, K.Ogane, S.Suzuki). Platelet activation and antiplatelet therapy in patients with ischemic stroke (S.Uchiyama et al.). Effect of delayed treatment with basic fibroblast growth factor on the survival of striatal spiny projection neurons after perinatal hypoxia-ischemia (D.E. Oorschot, M.M. Tompkins, K.A. Galvin). Platelet-activating factor enhances the expression of vascular endothelial growth factor in normal human astrocytes under hypoxia (H. Yoshida et al.). Changes in non-heme iron histochemistry in the ischemic brains of cats and Mongolian gerbils (H.Iwatsuki et al.). Nonheme ferric and ferrous iron accumulation in macrophages of rats and cats (R. Meguro, Y. Asano, K. Shoumura). Lack of association of 4G/5G polymorphism in plasminogen activator inhibitor-1 gene with stroke (M. Shoji et al.). Comparison of the effects of losartan and angiotensin converting enzyme inhibitor on nocturnal blood pressure in patients with stroke (N. Fujiwara et al.). Bacterial lipopolysaccharide induces retinoic acid-inducible gene-I in vascular endothelial cells (T.Imaizumi, H.Yoshida, K.Satoh). II. Neurodegeneration. cAMP-specific phosphodiesterases expression in Alzheimer's disease brains (S. Perez-Torres, G. Mengod). Mechanism of the white matter damage caused by virus infection (S. Semba, H.Sawa, K. Nagashima). A-Synuclein, synphilin-1 and inclusion body formation in A-synucleinopathies (K. Wakabayashi, H. Takahashi). Expression of A-and A-synucleins in cultered astrocytes and the effects of inflammatory cytokines (K. Tanji et al.). Widespread expression of A-synclein in neuronal cytoplasm and glial cells in the central and peripheral nervous systems in human (F. Mori et al.). Expression of A-synuclein in vascular endothelial and smooth muscle cells (W.Tamo et al.). L-DOPA-derived extracellular dopamine in the striatum with dopaminergic denervation: role of serotonergic neurons in L-DOPA metabolism (K.Kannari et al.). Fluoxetine reduces L-DOPA-derived extracellular DA in the 6-hydroxydopamine-lesioned rat striatum (H. Yamato et al.). Effects of benserazide, on L-DOPA-derived exrracellular dopamine levels and aromatic L-amino acid decarboxylase activity in the striatum of 6-hydroxydopamine-lesioned rats (H. Shen et al.). Hypertrophy of the medical globus pallidus in 6-hydroxydopamine-lesioned rats treated with levodopa (M. Tomiyama et al.). Increase of the striatal serotonergic fibers after nigrostriatal dopaminergic denervation in adult rats (T. Maeda et al.). Upregulation of the NR1 mRNA in the subthalamic nucleus of 6-hydroxydopamine lesioned-rats treated with L-DOPA (T. Kimura et al.). Risk factors for hip fracture among elderly patients with Parkinson's disease (Y. Sato et al.). Author index. Keyword index.
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