Principles of protein x-ray crystallography

著者

    • Drenth, Jan

書誌事項

Principles of protein x-ray crystallography

Jan Drenth

Springer New York, c2007

3rd ed

  • :pbk.

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内容説明・目次

内容説明

X-ray crystallography is an established method for studying the structure of proteins and other macromolecules. As the importance of proteins grows, researchers in many fields have found that a working knowledge of X-ray diffraction is an indispensable tool. In this new edition of his essential work, the internationally recognized researcher Dr. Jan Drenth offers an up-to-date and technically rigorous introduction to the subject, providing the theoretical background necessary to understand how the structure of proteins is determined at atomic resolution. New material in the 3rd edition includes a section on twinning, an additional chapter on crystal growth and a discussion of single-wavelength anomalous dispersion.

目次

Prefaces.- Crystallizing a Protein.- X-Ray Sources and Detectors.- Crystals.- The Theory of X-Ray Diffraction by a Crystal.- Average Reflection Intensity and Distribution of Structure Factor Data.- Special Forms of the Structure Factor.- The Solution of the Phase Problem by the Isomorphous Replacement Method.- Phase Improvement.- Anomalous Scattering in the Determination of the Protein Phase Angles and the Absolute Configuration.- Molecular Replacement.- Direct Methods.- Laue Diffraction.- Refinement of the Model Structure.- The Combination of Phase Information.- Checking for Gross Errors and Estimating the Accuracy of the Structural Model.- Tips and Tricks in Protein Crystallization.- Appendices.- References.- Index.

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詳細情報

  • NII書誌ID(NCID)
    BA79969016
  • ISBN
    • 9780387333342
    • 9781441922106
  • 出版国コード
    us
  • タイトル言語コード
    eng
  • 本文言語コード
    eng
  • 出版地
    New York, NY
  • ページ数/冊数
    xiv, 332 p.
  • 大きさ
    25 cm
  • 分類
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