DNA repair : new research

著者

    • Kimura, Sakura
    • Shimizu, Sora

書誌事項

DNA repair : new research

Sakura Kimura and Sora Shimizu, editors

(DNA and RNA : properties and modifications, functions and interactions, recombination and applications)(Cell biology research progress series)(Nova biomedical)

Nova Science Publishers, c2012

  • : hardcover

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

The maintenance of DNA integrity and genome stability is essential for the viability of cells and the life of organisms. The genetic material is constantly under attack from external environmental factors and endogenous metabolic products that can alter its chemical structure and nucleotides sequence. In this book, the authors present topical research in the study of DNA repair including topics such as DNA repair as the primary adaptive function of sex in bacteria and eukaryotes; DNA repair as a therapeutic target in breast cancer; DNA repair in the nervous system; targeting BRCA1 DNA repair pathway for cancer chemotherapy and DNA damage and repair during photodynamic therapy.

目次

  • DNA Repair as the Primary Adaptive Function of Sex in Bacteria & Eukaryotes
  • DNA Repair as a Novel Therapeutic Target in Breast Cancer
  • DNA Repair in the Nervous System: A New Research for Neurological Disorders
  • Targeting the BRCA1 DNA Repair Pathway for Cancer Chemotherapy
  • Functional Role for the c-Abl Tyrosine Kinase Signalling in the DNA Damage Response
  • From DNA Damage Response & Repair to Cancer: The Role of Nutrition
  • DNA Damage & Repair during Photodynamic Therapy
  • Translesion Synthesis Pathway & its Relevance in Cancer Therapy
  • Predictive Role of DNA Repair Genes in Tumor Response to Chemotherapy.

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