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TATEZUKI Junya, PAK Sujong, OHGAKI Fukutaro, TAKEMOTO Yasunori, MOCHIMATSU Yasuhiko NMC Case Report Journal 11 (0), 37-41, 2024-12-31

...Cerebral angiography revealed a dural arteriovenous fistula in the left parietal cranium with a feeder from the middle meningeal artery and a drainer into the main transverse sinus via a diploic vein....

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NAKADATE Masashi, KONDO Ryushi, ISHIHARA Shoichiro, UEMIYA Nahoko, KAKEHI Yoshiaki, HIDAKA Yukihiro, MINAMIMURA Kenzo, TOKUSHIGE Kazuo, TSUZUKI Nobusuke NMC Case Report Journal 11 (0), 99-102, 2024-12-31

...<p>M1 fenestration of the middle cerebral artery is rare. We present two patterns of acute thromboembolic conditions in M1 fenestrations treated with mechanical thrombectomy....

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OTSU Yusuke, KIKUCHI Jin, NAKAHARA Yoichiro, YOSHITAKE Hidenobu, KAJIWARA Sosho, SAKATA Kiyohiko, MORIOKA Motohiro NMC Case Report Journal 11 (0), 79-84, 2024-12-31

...TDA aneurysms may occur near the main trunk of the middle meningeal artery (MMA) where hemodynamic stress is high....

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Miyata Jun, Yamanashi Hirotomo, Kawashiri Shin-Ya, Soutome Sakiko, Arima Kazuhiko, Tamai Mami, Nonaka Fumiaki, Honda Yukiko, Kitamura Masayasu, Yoshida Koji, Shimizu Yuji, Hayashida Naomi, Kawakami Shigeru, Takamura Noboru, Sawase Takashi, Yoshimura Atsutoshi, Nagata Yasuhiro, Ohnishi Mayumi, Aoyagi Kiyoshi, Kawakami Atsushi, Saito Toshiyuki, Maeda Takahiro Ｊｏｕｒｎａｌ　ｏｆ　Ｅｐｉｄｅｍｉｏｌｏｇｙ 34 (5), 254-263, 2024-05-05

...launched a population-based prospective open-cohort study, the Nagasaki Islands Study (NaIS), which was conducted in Goto City, located in the remote islands of Nagasaki Prefecture, Japan, mostly involving middle-aged...

DOI Web Site PubMed 参考文献33件

大塚, 貞男, 村井, 俊哉 Reading and Writing 37 (5), 1183-1208, 2024-05

...From a large database of the most popular literacy exams in Japan, we retrospectively analyzed word- and text-level data for middle and high school students who had taken the exams during the same period...

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堀 功雅, 加藤 謙吾, 小野 英樹 鉄と鋼 110 (7), 513-521, 2024-05-01

...Fe–18mass%Cr alloy were measured at 1873 K by a chemical equilibration technique that uses the liquid immiscibility of the Fe–18mass%Cr alloy and Ag, yielding the following results:</p><p><img align="middle...

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Yoshida Naoko Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 47 (5), 878-885, 2024-05-01

...To eradicate substandard and falsified medicines, our group is conducting fact-finding investigations of medicines distributed in lower middle-income countries (LMICs) and on the Internet....

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金光 佳世子, 石井 真由美, 渡邊 恵里, 宮地 弘幸 薬学雑誌 144 (5), 529-537, 2024-05-01

...<p>In contrast to small molecules, middle molecules present a promising therapeutic modality owing to their elevated specificity, minimal adverse effects, capacity to target protein–protein interactions...

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宮地 弘幸, 前仲 勝実 薬学雑誌 144 (5), 527-528, 2024-05-01

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野村 研一, 飯倉 仁 有機合成化学協会誌 82 (5), 513-521, 2024-05-01

...Consequently, we discovered the clinical cyclic peptide LUNA18 (RAS inhibitor), demonstrating the value of cyclic peptides as a middle-size molecule modality.</p>...

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Alves-Cabratosa Lia, Elosua-Bayés Marc, Martí-Lluch Ruth, Blanch Jordi, Tornabell-Noguera Èric, Garcia-Gil Maria, Ponjoan Anna, Grau Maria, Ribas-Aulinas Francesc, Zacarías-Pons Lluís, Marrugat Jaume, Ramos Rafel Ｊｏｕｒｎａｌ　ｏｆ　Ａｔｈｅｒｏｓｃｌｅｒｏｓｉｓ　ａｎｄ　Ｔｈｒｏｍｂｏｓｉｓ 31 (5), 626-640, 2024-05-01

...These results support the guidelines on the utilization of risk age to explain heightened cardiovascular risk, particularly among individuals in middle age.</p>...

DOI Web Site PubMed 参考文献27件

南條 毅, 松元 彩香, 大下 拓真, 竹本 佳司 MEDCHEM NEWS 34 (2), 93-96, 2024-05-01

異常アミノ酸や大環状骨格等の特異構造を多く含むペプチド化合物は、中分子創薬における一大モダリティとして近年大きな注目を集めている。その多彩な誘導体を供給できる化学合成法の実現は重要な研究課題であり、特に伸長後のペプチド鎖に対する直接的な構造改変が実現できれば、すでに手元にある親ペプチド化合物を基に迅速な誘導体供給が可能となる。しかし、既存の手法は変換の足掛かりとして側鎖の反応性官能基を利用するも…

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島住 竜馬, 鳶巣 守 有機合成化学協会誌 82 (5), 450-460, 2024-05-01

...<p>As alternative strategy to transition metal-catalyzed cross-coupling, unimolecular fragment coupling (UFC) is defined as the reaction format, in which the atom(s) in the middle of the molecule is extruded...

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関 由起子, 桐淵 博 日本臨床救急医学会雑誌 27 (2), 93-101, 2024-04-30

<p><b>目的</b>：一次救命処置（basic life support；BLS）に関する実技講習受講経験のある教職志望学生に対して，学校事故の統計や学校事故の実例を講義に取り入れることにより，救命活動への自信がどのように変化するかを検討する。<b>方法</b>：A大学教育学部1年生対象の講義前後にアンケートを実施した。講義ではBLSの基本と効果に加え，体育活動時などにおける事故対応テキスト…

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CHEN Wanqiu, LU Hongtao, YING Yajing, LI Hongxia, SHEN Hui, CAI Jianming Ｊｏｕｒｎａｌ　ｏｆ　Ｎｕｔｒｉｔｉｏｎａｌ　Ｓｃｉｅｎｃｅ　ａｎｄ　Ｖｉｔａｍｉｎｏｌｏｇｙ 70 (2), 98-105, 2024-04-30

...The World Health Organization’s data shows that CKD affects about 10% of the world’s population, particularly in low- and middle-income countries....

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土井 真之, 楜澤 壮樹, 相澤 啓, 松本 春信, 川人 宏次 日本血管外科学会雑誌 33 (2), 111-114, 2024-04-26

<p>膝窩動脈捕捉症候群による膝窩動脈瘤は6%程度と少なく，比較的まれな疾患であり，診断および治療を適切に行う必要がある．今回われわれは，膝窩動脈捕捉症候群に伴う膝窩動脈仮性瘤の手術症例を経験した．症例は48歳女性．右下腿倦怠感，浮腫を主訴に来院した．造影CT検査で，膝窩動脈捕捉症候群Delaney分類II型を原因とする径31 …

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YOSHIDA Hiroaki, TANIGUCHI Ryoji, KONO Maho, TANI Mitsuru, TAKASUGI Norifumi, NAKANISHI Tamaki, ISHIKAWA Hiroki, HIMEJIMA Akio, NIWA Shinya, ISEKI Tomio Journal of Osaka Dental University 58 (1), 305-309, 2024-04-25

...The number of new patients was decreasing among middle‐aged and elderly patients; however, young female patients around the age of 20 were seeing an increase....

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YOSHIDA Keita, MOMOTA Yoshihiro Journal of Osaka Dental University 58 (1), 259-265, 2024-04-25

...After occlusion of the left middle cerebral artery for 45 minutes under sevoflurane anesthesia, the experimental group was divided into two groups as follows: "full opening immediately after occlusion...

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林 彰子 東京大学大学院教育学研究科紀要 63 9-16, 2024-04-25

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Ide Haruka, Kawasaki Yukako, Tamura Kentaro, Yoshida Taketoshi, Fujihara Ryosuke, Hara Akane, Taguchi Masato Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 47 (4), 861-867, 2024-04-20

...NONMEM analysis provided the following final model of oral clearance: CL/F = 0.00603∙<i>WT</i>∙<img align="middle" src="....

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