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表紙
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日本環境変異原学会第37回大会(JEMS2008)コミュニケーション〜ヒト・環境・リスク〜 (併催)遺伝毒性アセスメント国際シンポジウム プログラム・要旨集(標題紙)
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大会長あいさつ
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3
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大会案内
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4-5
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大会内容
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6
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受付・発表方法のご案内
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7
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会場アクセス
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8-10
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37th Annual Meeting of the Japanese Environmental Mutagen Society Communication -People, Environment and Risk- and International Symposium on Genotoxicity Assessment -New Concept, Strategy and Regulation- Program & Abstracts(Title page)
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Message from the President of the Conference
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13
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Conference Information
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14-15
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Conference Schedule
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16
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Registration and Presentation Guideline
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17
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日本環境変異原学会第37回大会(JEMS2008)プログラム(中扉)
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日本環境変異原学会第37回大会(JEMS2008)プログラム
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21-42
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37th Annual Meeting of the Japanese Environmental Mutagen Society Communication -People, Environment and Risk- Program(Divisional title)
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37th Annual Meeting of the Japanese Environmental Mutagen Society Communication -People, Environment and Risk- Program
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45-70
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International Symposium on Genotoxicity Assessment -New Concept, Starategy and Regulation- Program(Divisional title)
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71
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International Symposium on Genotoxicity Assessment -New Concept, Starategy and Regulation- Program
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72-74
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日本環境変異原学会第37回大会抄録(中扉)
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AW Chemical and Biological Approaches for Detecting Environmental Causes of Cancer(Award Lecture)
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77
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SE Activation mechanism of environmental mutagens and its application to antitumor research(Award Lecture)
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78
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EN gpt delta transgenic rodents mutation assays: detection and molecular analysis of point mutations and deletions(Award Lecture)
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79
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S1-1 Global Environment/Living Organisms/Chemical(Symposium 1: Environmental Issues and Genotoxicity)
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80-82
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S1-2 Implications of Soil and Air Pollution with Mutagens in the Incidence of Lung Cancer(Symposium 1: Environmental Issues and Genotoxicity)
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83
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S1-3 Genotoxicity of Environmental Air Pollutants(Symposium 1: Environmental Issues and Genotoxicity)
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84
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S1-4 Genotoxic assessment of small mammals at an illegal dumpsite of industrial waste(Symposium 1: Environmental Issues and Genotoxicity)
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85
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S2-1 Transgenerational Genomic Instability in Mice(Symposium 2: The Tutikawa Fund Memorial Symposium -In Vivo Gene Mutation and Heritable Effects-)
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86
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S2-2 gpt delta transgenic mouse and rat for analysis of in vivo mutagenesis(Symposium 2: The Tutikawa Fund Memorial Symposium -In Vivo Gene Mutation and Heritable Effects-)
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87
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S2-3 A large-scale mouse ENU-mutageneis project(Symposium 2: The Tutikawa Fund Memorial Symposium -In Vivo Gene Mutation and Heritable Effects-)
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88
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S2-4 Design of an in vivo gene mutation assay for use in human risk assessment(Symposium 2: The Tutikawa Fund Memorial Symposium -In Vivo Gene Mutation and Heritable Effects-)
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89
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S3-1 Collaborative Study on the Toxicogenomics in JEMS/MMS(Symposium 3: Current Research of Omics)
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90
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S3-2 Establishment of Integrated Cancer Diagnostics based on Cancer Genomics and Proteomics(Symposium 3: Current Research of Omics)
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91
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S3-3 Application of metabolomics to drug development(Symposium 3: Current Research of Omics)
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92
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S3-4 Characteristics of epigenetic alterations reveled by epigenome analysis(Symposium 3: Current Research of Omics)
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93
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S4-1 Genetic Instability Inducers in Saccharomyces cerevisiae : Mutation in sanitizing enzymes for deaminated nucleotide lesions, HAM1, and a non-mutagenic carcinogen, Phenyl hydroquinone (PHQ)(Symposium 4: DNA Repair and Genomic Instability)
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94
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S4-2 DNA double strand break repair and genomic instability(Symposium 4: DNA Repair and Genomic Instability)
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95
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S4-3 8-Oxoguanine contributes to the genome instability and diversity through enhancing the homologous recombination(Symposium 4: DNA Repair and Genomic Instability)
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96
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S4-4 Functions of the Bloom syndrome responsible gene product in DNA replication and sister chromatid cohesion(Symposium 4: DNA Repair and Genomic Instability)
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97
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S5-1 Benefits and drawbacks of in vitro toxicology testing(Symposium 5: In Vitro Genotoxicity Tests -Pros and Cons-)
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98
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S5-2 In vitro genotoxicity tests discussed in ICH and ECVAM(Symposium 5: In Vitro Genotoxicity Tests -Pros and Cons-)
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99
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S5-3 The in Vitro Genetic Toxicity (IVGT) Testing ILSI-HESI initiative on relevance and follow-up of positive results in in vitro genetic toxicity testing(Symposium 5: In Vitro Genotoxicity Tests -Pros and Cons-)
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100
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S5-4 In vitro genotoxicity testing : a challenge for cosmetic industry(Symposium 5: In Vitro Genotoxicity Tests -Pros and Cons-)
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101
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S6-1 Environmental issues and chemical risk assessment(Symposium 6: Environmental issues and risk assessment)
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102-104
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S6-2 Genetic Toxicity Assessment: Need for an Integrated In Vivo Testing Strategy(Symposium 6: Environmental issues and risk assessment)
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105
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S6-3 Environmental Effects of Pharmaceuticals and its Risk Assessment(Symposium 6: Environmental issues and risk assessment)
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106
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P-001 / O-08 Mutagenicity induced by a single 8-oxoguanine in genome of human lymphoblastoid cells(Poster Session)
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107
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P-002 / O-01 Significance of DNA adductome analysis in in vitro microcucleus test(Poster Session)
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107
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P-003 Formation of aminophenylnorharman-phosphoester (APNH-PE) adducts(Poster Session)
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108
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P-004 Formation of an RNA adduct derived from aminophenylnorharman (APNH), a novel endogenous mutagen and carcinogen(Poster Session)
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108
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P-005 / O-02 Efficiency and fidelity of translesion DNA synthesis across 3-nitrobenzanthrone-DNA-adducts(Poster Session)
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109
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P-006 8-Hydroxyguanine and translesion synthesis DNA polymerases(Poster Session)
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109
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P-007 Characterization of human DNA polymerase κ(Poster Session)
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110
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P-008 Quantitative analysis of Translesion DNA Synthesis across Site-specific 4-Aminobiphenyl Adducts in Human Cells(Poster Session)
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110
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P-009 Effects of methyl DNA lesions on human RNA polymerase II-transcription(Poster Session)
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111
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P-010 Oxidative and nitrative DNA damage in mice with oncogenic ras(Poster Session)
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111
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P-011 Study on the mutagenic mode of action by toxicogenomics approach(Poster Session)
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112
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P-012 Carcinogenic mechanism of an environmental pollutant 2-nitrotoluene(Poster Session)
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112
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P-013 Possible mechanism underlying the carcinogenic effects of Bisphenol A(Poster Session)
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113
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P-014 Metal-mediated DNA damage induced by methylene blue in relation to the carcinogenicity(Poster Session)
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113
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P-015 Oxidative Stress-Induced Tumorigenesis in the Small Intestine of the Mice with Defects in DNA Repair-Related Genes(Poster Session)
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114
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P-016 Analysis of alkyltransferase-like (Atl) protein of Thermus thermophilus(Poster Session)
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114
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P-017 Accumulation of DNA double-strand breaks in senescent human fibroblast cells(Poster Session)
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115
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P-018 Genomic Stability of Immortalized Human Mesenchymal Stem Cells (Non-random Loss of Chromosome 13 in Culture)(Poster Session)
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115
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P-019 Repair pathway of O^4-alkylthymine(Poster Session)
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116
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P-020 Mutagenicity of N-Nitrosodialkylamines by Chemical Model for Cytochrome P450; Ruthenium Porphyrin and Oxidant(Poster Session)
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116
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P-021 Genotoxic activation of 2-phenylbenzotriazole-type compounds by human cytochrome P450 1A1 and N-acetyltransferase expressed in Salmonella typhimurium umu strains(Poster Session)
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117
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P-022 Child-adult differences in evaluation of in vivo genotoxicity of acrylamide(Poster Session)
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117
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P-023 Unbiased quantification of oxidative modifications of cysteine thiols by double labeling approach using isotope amino acids and affinity Tags (DLIAA)(Poster Session)
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118
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P-024 Aryl hydrocarbon receptor and estrogen receptor cross-talk mediated gene expression by halogenated polycyclic aromatic hydrocarbons(Poster Session)
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118
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P-025 / O-09 Screening for Transformation Related Genes Using Microarray Analysis(Poster Session)
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119
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P-026 Evaluation of endocrine disruptors using reporter yeasts expressing human androgen receptor and thyroid hormone receptor(Poster Session)
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119
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P-027 Agonistic and Antagonistic Activities of various Chemicals in Reporter Yeasts Expressing Estrogen Receptors α and β(Poster Session)
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120
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P-028 Expression of DNA methyltransferases in testicular germ cells of the offspring of male mice prenatally exposed to diethylstilbestrol(Poster Session)
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120
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P-029 (-)-Epigallocatechin (EGC), one of the major green tea catechins, has a weak mutagenic activity(Poster Session)
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121
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P-030 Mutagenicity of DMSO extract of mainstream smoke from major cigarettes in Japan with smoking machine(Poster Session)
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121
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P-031 Mutagenicity of azabicycloheptane N-nitrosamines using the Ames/Salmonella assay(Poster Session)
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122
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P-032 Bacterial mutagenicity of chlorinated polycyclic aromatic hydrocarbons(Poster Session)
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122
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P-033 Analysis of mutagenic photoproduct formed by UV-irradiation on maltol or ethylmaltol solution(Poster Session)
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123
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P-034 Screening and mechanism study of endogenous mutagens using modified Ames tester strains(Poster Session)
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123
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P-035 Effect of indium chloride on micronucleus induction(Poster Session)
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124
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P-036 The clastogenic potential of benzyl acetate : mouse lymphoma assay and chromosome aberration test using CHL/IU cells(Poster Session)
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124
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P-037 Evaluation of genotoxicity of 3,6-Dinitrobenzo[e]pyrene in human cell lines(Poster Session)
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125
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P-038 In vitro genotoxicity assessment of wood smoke flavors(Poster Session)
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125
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P-039 Topoisomerase II inhibition invovled in DNA Double-Strand Breaks by Emodin and its genotoxocity(Poster Session)
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126
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P-040 UVA irradiation enhances phosphorylation of histone H2AX induced by 9,10-phenanthrenequinone(Poster Session)
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126
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P-041 / O-11 Flow cytometry analysis for γH2AX induction after treatment with CDDP, MMC, MMS and CPT-11(Poster Session)
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127
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P-042 H2AX was not phosphorylated by five aneugens in CHL, CHO and V79 cells(Poster Session)
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127
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P-043 UVB-exposed chlorinated bisphenol A generates phosphorylated histone H2AX in human skin cells(Poster Session)
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128
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P-044 Silver particles induces phosphorylation of histone H2AX(Poster Session)
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128
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P-045 Evaluation of DNA damaging potency by coadministration of isoflavones and sodium nitrite in mouse gastric mucosa(Poster Session)
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129
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P-046 Effect of aging on the spontaneous and cyclophosphamide-induced micronucleus frequencies in male rats with age(Poster Session)
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129
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P-047 In vivo mutagenicity of madder color and its constituents using gpt delta rats(Poster Session)
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130
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P-048 / O-05 Acrylamide and Glycidamide-induced gene mutations and mitochondrial gene expression profiles in transgenic mice(Poster Session)
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130
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P-049 Genotoxicity of azo dyes metabolized by intestinal bacteria in mouse, rat and human(Poster Session)
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131
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P-050 Relationship between micronucleus formation and pathological findings induced by mitomycin C in rat skin(Poster Session)
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131
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P-051 Formation of nitrosamine in diabetic animals and the change of the genotoxicity in several organs(Poster Session)
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132
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P-052 Change of genotoxity of acrylamide in diabetic rats(Poster Session)
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132
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P-053 Mutagenicity of PBTA-6 and benzo[a]pyrene in the gill and hepatopancreas of rpsL transgenic zebrafish(Poster Session)
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133
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P-054 Increase of structural-chromosomal aberrations and micronuclei caused by mitomycin C treatment in embryo cells of zebrafish(Poster Session)
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133
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P-055 Effects of environmental cigarette smoke (ECS) on the viability of Drosophila exposed at the third instar larval stage and urate contents in larvae(Poster Session)
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134
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P-056 Evaluation of Genotoxicity of Intermediate Frequency Magnetic Fields by Mouse Lymphoma Assay(Poster Session)
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134
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P-057 Effect of static magnetic fields on production of 8-OHdG in mice bone marrow cells(Poster Session)
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135
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P-058 Evaluation of Genotoxicity of Intermediate Frequency Magnetic Fields by in vitro Micronucleus Test(Poster Session)
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135
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P-059 Genotoxicity of nanomaterials(Poster Session)
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136
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P-060 / O-06 Basic examination of carbon nanotube genotoxicity(Poster Session)
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136
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P-061 Analysis of DNA adducts in the lung of mice exposed to multi-wall carbon nanotube(Poster Session)
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137
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P-062 Evaluation of genotoxic risk and oxidative DNA damage in human keratinocytes exposed to amorphous nano-silica(Poster Session)
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137
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P-063 Influence of physicochemical property of nano-silicas on in vivo biological behavior (1)(Poster Session)
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138
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P-064 Influence of physicochemical properties of nano-silica particles on in vivo biologic behavior (2)(Poster Session)
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138
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P-065 Development of an in vitro safety evaluation system for nanomaterials : -1- Titanium dioxide(Poster Session)
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139
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P-066 Development of an in vitro safety evaluation system for nanomaterials : -2- Fullerene C_<60>(Poster Session)
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139
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P-067 Development of an in vitro safety evaluation system for nanomaterials : -3- Single-walled carbon nanohorns and multi-walled carbon nanotubes(Poster Session)
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140
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P-068 Sunscreen Titanium dioxide Nanoparticles (T-Lite^<TM> SF) showed no Genotoxic Effectsin Modified Standard Assays in vitro and in vivo(Poster Session)
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140
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P-069 Is titanium dioxide really safe? : Particle size-dependent induction of DNA damage(Poster Session)
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141
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P-070 Cytotoxicity and genotoxicity of eleven size-different polystyrene particles(Poster Session)
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141
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P-071 Genotoxicity of nanoparticles in in vivo assay systems(Poster Session)
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142
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P-072 Development of Novel Radioprotectors : Vitamin E Derivatives Having a Basic Moiety(Poster Session)
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142
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P-073 Novel polyselenodisulfides showing oxidative DNA damage-protecting activity(Poster Session)
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143
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P-074 Conformationally Constrained Epicatechin Analogue as a Promising Antioxidant(Poster Session)
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143
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P-075 / O-07 Protamine-Induced DNA Conformational Change and Its Effect on Radiosensitivity(Poster Session)
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144
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P-076 Suppression of SOS-inducing activity of chemical mutagens by coumarins from Angelica dahurica(Poster Session)
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144
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P-077 Suppressive effect of nobiletin and its metabolite on MeIQ-induced SOS response(Poster Session)
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145
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P-078 Suppression of SOS-inducing activity of chemical mutagens by metabolites from microbial transformation of (-)-isolongifolene(Poster Session)
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145
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P-079 Antimutagenicity of fragrant ingredients in Katsura-uri Japanese pickling melon(Poster Session)
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146
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P-080 Effects of natural antioxidants on cell growth and genotoxicity induced hydrogen peroxide in human lymphoblastoid TK6 cells(Poster Session)
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146
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P-081 TCDD represses benzo[a]pyrene-DNA adduct formation in HepG2 cell(Poster Session)
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147
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P-082 Inhibition of benzo[a]pyrene-DNA adducts by chrysoeriol, a dietary methoxyflavonoid, in MCF-7 cells(Poster Session)
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147
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P-083 Potential of royal jelly-specific fatty acid, 10-hydroxydecenoic acid as a cancer chemopreventive agent(Poster Session)
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148
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P-084 Evaluation of the anti-mutagenicity of food components against chemicals induced DNA damages(Poster Session)
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148
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P-085 Genotoxicity of Dental Materials and Protective Role of Chitosan(Poster Session)
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149
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P-086 Examination of the inhibition of 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) absorption in intestinal tract by intake of cellulose(Poster Session)
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149
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P-087 Alteration of 3-methylthiopropionic acid ethyl ester in stomach to its hydrolyzed antimutagenic product(Poster Session)
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150
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P-088 Juice of Vitis coignetiae Pulliat (Yamabudo) inhibits the mutagenicity of heterocyclic amines and MeIQx- and PhIP-DNA adducts formation in C57BL mice(Poster Session)
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150
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P-089 Urea generates a positive reaction in the 8-OHdG analysis by ELISA method(Poster Session)
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151
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P-090 Genotoxicity High throughput Screening Using Bacteria : Automation of the SOS/umu test(Poster Session)
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151
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P-091 Improved Luminescent umu Test Method and Its Application to Measurement of Total Suspended Particulates and Gaseous Components(Poster Session)
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152
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P-092 Attempt of genotoxicity test kit using umu tester strain expressing human cytochrome P450 enzyme(Poster Session)
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152
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P-093 / O-10 Evaluation of high-throughput genotoxicity test system using umu tester strain expressing human cytochrome P450 enzyme(Poster Session)
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153
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P-094 Further improvement of high-throughput fluctuation Ames test (Part IV)(Poster Session)
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153
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P-095 Automation of Bacterial Reverse Mutation Assay (Ames Assay) : Development of a Reagents Dispenser Device Part(Poster Session)
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154
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P-096 Photomutagenicity test on phototoxic chemicals with bacteria(Poster Session)
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154
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P-097 A Preliminary Study on the in vitro Covalent DNA Binding Assay using Radiolabeled Compounds(Poster Session)
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155
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P-098 In vitro genotoxicity test system based on p53R2 gene expression in a human cell line(Poster Session)
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155
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P-099 Validation of in vitro Comet Assay Protocol(Poster Session)
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156
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P-100 Is in vitro comet assay a sensitive procedure to detect genotoxicity?(Poster Session)
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156
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P-101 Ability of comet assay to detect sperm DNA damage using fresh and freeze-dried mouse and human spermatozoa(Poster Session)
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157
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P-102 The Mouse Lymphoma Assay detects recombination, deletion, and aneuploidy(Poster Session)
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157
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P-103 The in vitro micronucleus test for a little sample(Poster Session)
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158
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P-104 High content flow cytometry-based micronucleus scoring method is applicable to CHO-K1 cells(Poster Session)
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158
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P-105 Effect of recovery time in the chromosomal aberration test using cultured mammalian cells(Poster Session)
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159
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P-106 Investigation of test conditions for chromosomal aberration test in CHL/IU : follow-up time course of aberrant cells(Poster Session)
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159
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P-107 / O-12 HepG2 transformants expressing a series of human cytochrome P450 isoforms for genotoxicity testing(Poster Session)
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160
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P-108 An evaluation of Bhas 42 cell transformation assay for the detection of chemical carcinogenicity(Poster Session)
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160
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P-109 An investigation on the dose setting for the Bhas 42 cell transformation assay(Poster Session)
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161
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P-110 Development of an automatic plate handling system for high-throughput Bhas 42 cell transformation assay(Poster Session)
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161
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P-111 Reduction of false positives in in vitro genotoxicity assays(Poster Session)
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162
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P-112 Application of Cytotoxicity Biomarkers in DNA Damage Assessment(Poster Session)
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162
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P-113 Correlation between the results of in vitro and in vivo chromosome damage tests(Poster Session)
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163
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P-114 / O-13 Trials of Comet/Micronucleus Combined Assay(Poster Session)
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163
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P-115 Comet and micronucleus assay in rat liver tissue for the early screening of genotoxic hepatocarcinogen(Poster Session)
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164
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P-116 Changes of 8-OHdG levels on Malignant Peritoneal Mesothelioma and 5-Aminolevulinic Acid-Mediated Photodynamic Diagnosis : A Pilot Study used F344 rats(Poster Session)
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164
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P-117 Collaborative Study of Liver Micronucleus Assays in Young Rats : Investigation of Twice dosing design by JEMS MMS Collaborative Study Group(Poster Session)
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165
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P-118 / O-14 Cyclophosphamide and Etoposide Canine Studies Demonstrate the Cross-Species Potential of the Peripheral Blood Micronucleated Reticulocyte Endpoint(Poster Session)
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165
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P-119 / O-15 Development of an in vivo micronucleus assay using rat glandular stomach : study on the time- and dose-dependency of the induction of micronucleated epithelial cells(Poster Session)
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166
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P-120 Difference in mutagenicity of structural isomers 2,4-DAT and 2,6-DAT in the target organ for carcinogenicity of F344 gpt delta transgenic rat(Poster Session)
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166
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P-121 The effect of post-irradiation on ENU mutagenesis in thymocytes of B6C3F1 gpt-delta mice(Poster Session)
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167
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P-122 Validation of Transgenic Rodent Gene Mutation Assays using DNA Sequence Data(Poster Session)
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167
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P-123 / O-16 Development of a novel in vivo gene mutation assay using the Pig-A gene as an endogenous reporter, Part 1 : Rat Studies(Poster Session)
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168
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P-124 Development of a novel in vivo gene mutation assay using the Pig-A gene as an endogenous reporter, Part 2 : Mouse Studies(Poster Session)
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168
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P-125 Validation of a Gene Mutation Assay using a Pig-A gene(Poster Session)
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169
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P-126 Mutagenicity of extract prepared from surface soil of residential and industrial areas in Shizuoka prefecture, and detection of mutagens(Poster Session)
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169
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P-127 Mutagenicity and PAH Content of Forest or Planting Soil(Poster Session)
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170
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P-128 Development of two dimensional analytical method of 3,6-dinitrobenzo[e]pyrene with on-line reduction in soil and tea leaves(Poster Session)
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170
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P-129 Genome Stress, Ecological Decrease and Biological Concentration of Radionuclides in Organisms after Chernobyl Catastrophe(Poster Session)
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171
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P-130 Basic examination of immunotoxicity of urban aerosols(Poster Session)
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171
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P-131 Mutagenicity of Total Suspended Particulates and Gaseous Components Simultaneously Collected in Summer and Winter at 10 Sites in Japan(Poster Session)
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172
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P-132 Tumor-promoting potential of airborne particulate and gaseous matter in winter at ten places in Japan(Poster Session)
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172
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P-133 Quantitative determination of 2-phenylbenzotriazole-type mutagens in river water(Poster Session)
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173
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P-134 Genotoxicity of polluted ground water in the Noyyal River basin, Tamilnadu, India(Poster Session)
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173
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P-135 / O-03 Detection of 4-OHE-DNA adducts in human lung tissue(Poster Session)
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174
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P-137 The characteristics of chromosome abnormalities of mouse thymic lymphoma caused by X-irradiation at 1 week of age(Poster Session)
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174
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P-138 Availability of DNA damage, N^2-ethylidene-dG, as a biomarker of acetaldehyde exposure(Poster Session)
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175
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P-139 Analysis of N^ε-ethyllysine in proteins by NCI-GC/MS as a biomarker for acetaldehyde exposure : detection in exfoliated human oral cells(Poster Session)
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175
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P-140 Measurement of Hb-associated acetaldehyde in Aldh2 knockout mice exposed to acetaldehyde(Poster Session)
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176
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P-141 Space Experiment : Analysis of Radiation Effects by LOH Detection System(Poster Session)
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176
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P-142 Simultaneous analysis of various oxidative DNA adducts in human tissues using LC-MS/MS(Poster Session)
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177
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P-143 / O-04 Detection and evaluation of DNA adducts in human pancreas and spleen by the DNA adductomics methodology(Poster Session)
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177
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P-144 Proteomics approach to find new biomarkers for genotoxicity in urine samples(Poster Session)
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178
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P-145 Comparison between EU and German MAK Classifications of Chemicals on Mutagenicity(Poster Session)
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178
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P-146 The seclusion hypothesis of Y-chromosome : deduction from the partial translocation of Y-linked genes to X chromosome in two XO species of the Ryukyu spiny rat and generalized distal localization of Y-linked genes during miniaturization of Y chromosomes(Poster Session)
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179
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P-147 Synthesis and reactivity of vitamin B2 derivatives photooxidizing guanine(Poster Session)
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179
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P-148 Tumor-promoting potential of preservatives in cell transformation assay using Bhas 42 cells(Poster Session)
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180
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P-149 Isolation of a Y-family DNA polymerase eta of a worm living in deep sea(Poster Session)
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180
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P-150 Antimutagenic effect of hot water extract from Agaricus blazei Murill(Poster Session)
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181
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T-01 Mutagenesis and Instability of Mouse Primordial Germ Cells with N-Ethyl-N-nitrosourea(The Tutikawa Fund Memorial Poster Session)
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182
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T-02 Can in vivo Comet assay predict well rodent carcinogenicity?(The Tutikawa Fund Memorial Poster Session)
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182
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T-03 Collaborative Study on the Toxicogenomics in JEMS/MMS/2008 : Quantitative Real-Time PCR Analysis on Mouse Liver Carcinogens(The Tutikawa Fund Memorial Poster Session)
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183
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T-04 Chromosome Aberrations in Mouse Sperm Nuclei Exposed to Topoisomerase II Inhibitors during Fertilization(The Tutikawa Fund Memorial Poster Session)
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183
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T-05 Evaluation of a specific method for micronucleus test into general toxicity test and combination method of triple- dose micronucleus test and comet assay(The Tutikawa Fund Memorial Poster Session)
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184
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T-06 In vivo Skin Micronucleus Assay -Development and Validation- : CSGMT/JEMS・MMS Collaborative Study for the skin micronucleus assay(The Tutikawa Fund Memorial Poster Session)
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184
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T-07 Detection by dual color fluorescence in situ hybridization of in vivo chromosome damage in rat hepatocytes(The Tutikawa Fund Memorial Poster Session)
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185
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T-08 Hypermutability of Atm-null mice in the somatic stem cells before and after exposure to ionizing radiation(The Tutikawa Fund Memorial Poster Session)
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185
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T-09 Collaborative study on the toxicogenomics in JEMS MMS/2008 II : Validation of the TaqMan Low Density Array for a rapid screening of genotoxic carcinogens(The Tutikawa Fund Memorial Poster Session)
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186
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T-10 Genome mapping of damaged chromosome regions induced by ionizing irradiation using DNA microarray analysis(The Tutikawa Fund Memorial Poster Session)
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186
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T-11 Consideration about data analysis for international validation on in vitro comet assay(The Tutikawa Fund Memorial Poster Session)
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187
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T-12 Analysis of the spontaneous mutagenesis in gpt delta transgenic rodents(The Tutikawa Fund Memorial Poster Session)
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187
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T-13 Development of the micronucleus assay system using medaka fish (Oryzias latipes) as an alternative to the mammalian system(The Tutikawa Fund Memorial Poster Session)
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188
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T-14 Chemical responsiveness in suncus as a primitive species of mammals(The Tutikawa Fund Memorial Poster Session)
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188
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International Symposium on Genotoxicity Assessment -New Concept, Strategy and Regulation- Abstracts(Divisional title)
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IS I-1 A New OECD Test Guideline (TG487) : In Vitro Mammalian Cell Micronucleus Test (MNvit)(Session I: In Vitro Tests)
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191
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IS I-2 Cytogenetic assays, thresholds and off-target effects(Session I: In Vitro Tests)
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192
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IS I-3 Overview of the latest recommendations for interpreting data from the mouse lymphoma assay(Session I: In Vitro Tests)
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193
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IS II-1 Validation of a multi-endpoint assay in rats : bone marrow micronucleus, comet and flow cytometric peripheral blood micronucleus(Session II: In Vivo Tests)
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194
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IS II-2 The Utility Transgenic Rodent Gene Mutation Assays(Session II: In Vivo Tests)
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195
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IS II-3 In Vivo Comet Assay : Update on the On-Going Validation Coordinated by JaCVAM(Session II: In Vivo Tests)
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196
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LS-1 The Development of China GLP Compliance Program and Genotoxicity Assessment Guideline for Pharmaceuticals(Luncheon Session: Genotoxicity Assessment in Asian Countries)
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197
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LS-2 Genotoxicity Assessment in Korea and Related Issues(Luncheon Session: Genotoxicity Assessment in Asian Countries)
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198
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LS-3 APPLICATION OF GOOD LABORATORY PRACTICES (GLP) IN GENETIC TOXICOLOGY STUDIES : INDIAN REGULATORY SCENARIO(Luncheon Session: Genotoxicity Assessment in Asian Countries)
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199
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LS-4 Who, What, When, Where, Why and How to Run Genotoxicity Testing for Environment(Luncheon Session: Genotoxicity Assessment in Asian Countries)
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200
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LS-5 Genotoxic Potential of Areca Nut-Containing Polyphenols: Is It Real?(Luncheon Session: Genotoxicity Assessment in Asian Countries)
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201
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IS III-1 Human genotoxicity tests during pharmaceutical development(Session III: Human Tests)
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202
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IS III-2 Flow cytometric approaches for studying cytogenetic damage and gene mutation across species of toxicological interest, including man(Session III: Human Tests)
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203
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IS III-3 Development of Genetic Instability and Somatic Mutation Assays in Radiation-Exposed Individuals(Session III: Human Tests)
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204
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IS IV-1 Regulatory Issues on Pharmaceutical chemicals : revision of ICH S2(Session IV: Regulatory Issues and Risk Assessment)
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205
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IS IV-2 Weight of Evidence Approach in Hazard Classification on Genotoxicity(Session IV: Regulatory Issues and Risk Assessment)
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206
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IS IV-3 Enhancing the Utility of Genotoxicity Data for Human Risk Assessment(Session IV: Regulatory Issues and Risk Assessment)
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207
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Author Index(Divisional title)
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Author Index
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211-220
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協賛企業・団体
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221
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Acknowledgement
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222
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奥付
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裏表紙
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