CiNii Articles - クラスターDNA損傷

1

Studying the effects of galactic cosmic radiation on astro- and microbiological model systems [in Japanese]

藤森亮 , Beblo-Vranesevic Kristina , Leuko Stefan , Moller Ralf

生体の科学 69(2), 157-161, 2018-03

Ichushi Web
2

細胞の運命を左右する「クラスターDNA損傷」の探求 : FRETを活用して (特集放射線による生物影響のメカニズムに迫る) [in Japanese]

赤松憲

放射線と産業 (143), 21-25, 2017-12
3

P-005(O-05) Nucleotide excision repair suppresses mutagenesis induced by clustered oxidative DNA adducts in the human genome(Poster Sessions) [in Japanese]

Sassa Akira , Kamoshita Nagisa , Kanemaru Yuki , Honma Masamitsu , Yasui Manabu

日本環境変異原学会大会プログラム・要旨集 (44), 95, 2015

NDL Digital Collections
4

Radiation-induced DNA damage and DNA repair [in Japanese]

松田外志朗

DNAは, 放射線をはじめ紫外線や活性酸素等の要因により多様な損傷を受ける. 生体は, DNA損傷の種類に応じて損傷を修復する複数のDNA修復機構を有している. DNA損傷は, 常に確実に修復されるわけではなく, 修復できなかった場合に細胞死をもたらすシステムやDNA損傷を乗り越えてDNA合成を行うシステムも存在する. また, DNA損傷が適切に修復されなければ, 突然変異が誘発され, がん化の要 …

近畿大学原子力研究所年報 51, 15-25, 2014

IR
5

P-017(O-14) Numerical genotoxic effects of clustered 8-oxoguanine DNA adducts locally introduced into the genome(Poster Sessions) [in Japanese]

Sassa Akira , Kamoshita Nagisa , Kanemaru Yuki , Honma Masamitsu , Yasui Manabu

日本環境変異原学会大会プログラム・要旨集 (43), 99, 2014

NDL Digital Collections
6

O-14(P-017) Numerical genotoxic effects of clustered 8-oxoguanine DNA adducts locally introduced into the genome(Platform Session 3) [in Japanese]

Sassa Akira , Kamoshita Nagisa , Kanemaru Yuki , Honma Masamitsu , Yasui Manabu

日本環境変異原学会大会プログラム・要旨集 (43), 87, 2014

NDL Digital Collections
7

The role of PolI in processing clustered DNA damage [in Japanese]

SHIKAZONO Naoya , NOGUCHI Miho , URUSHIBARA Ayumi , YOKOYA Akinari

Clustered DNA damage, defined as two or more lesions within one to two helical turns of DNA induced by a single radiation track, is a unique feature of ionizing radiation. We have studied the biologic …

The Japan Radiation Research Society Annual Meeting Abstracts 2011(0), 212-212, 2011

J-STAGE
8

Order effect of base excision processes to repair clustered DNA damage. [in Japanese]

SHIRAISHI Iyo , SHIINA Takuya , SUGAYA Yuki , SHIKAZONO Naoya , YOKOYA Akinari

In a living cell, a multiply damaged site in DNA is thought to be repaired by several different repair pathways simultaneously or sequentially. Under this situation the final cellular response to the …

The Japan Radiation Research Society Annual Meeting Abstracts 2011(0), 201-201, 2011

J-STAGE
9

Analysis of spatial distribution of DNA damage around the radiation track [in Japanese]

WATANABE RITSUKO , SHIINA TAKUYA , YOKOYA Akinari

We have estimated the DNA damage spectrum by track structure simulation method. The simulation result shows that the increase of the complexity of initial DNA damage and cell lethality show partially …

The Japan Radiation Research Society Annual Meeting Abstracts 2011(0), 198-198, 2011

J-STAGE
10

Yields of isolated and clustered DNA damage in cultured cells irradiated with heavy particle beams [in Japanese]

SHIMAZAKI-TOKUYAMA Yuka , INOUE Yuko , FURUSAWA Yoshiya , IDE Hiroshi , TERATO Hiroaki

Ionizing radiations induce a variety of oxidative DNA damage including isolated and clustered DNA damage. The latter damage is a specific one with ionizing radiation, which might be involved in expres …

The Japan Radiation Research Society Annual Meeting Abstracts 2011(0), 193-193, 2011

J-STAGE
11

Dependence of the yields of AP sites and AP clusters produced in pUC18 plasmid DNA on scavenging capacity and radiation quality and LET [in Japanese]

SHIINA TAKUYA , SUGAYA YUKI , SHIRAISHI IYO , WATANABE RITSUKO , YOKOYA AKINARI , TSURUOKA CHIZURU , SUZUKI MASAO

The object of the study is to reveal whether the induction process of an abasic site (AP site) and the clustered DNA damage which contain AP sites (AP cluster) depends on ionizing density of radiation …

The Japan Radiation Research Society Annual Meeting Abstracts 2011(0), 191-191, 2011

J-STAGE
12

A novel technique using DNA denaturation-annealing to detect multiply induced base lesions in plasmid DNA molecules [in Japanese]

YOKOYA Akinari , SHIKAZONO Naoya , FUJII Kentaro

Many studies have determined yields of base lesions arising in DNA by irradiation of ionizing radiation. These studies have mainly used base excision repair proteins as an enzymatic probe. The base le …

The Japan Radiation Research Society Annual Meeting Abstracts 2010(0), 124-124, 2010

J-STAGE
13

Mutations induced by clustered DNA damage containing 8-oxoG [in Japanese]

NOGUCHI Miho , URUSHIBARA Ayumi , YOKOYA Akinari , SHIKAZONO Naoya

A single track of ionizing radiation is considered to induce closely spaced DNA lesions (clustered DNA damage) including single strand breaks (SSBs) AP sites, and base lesions. It has been hypothesize …

The Japan Radiation Research Society Annual Meeting Abstracts 2010(0), 240-240, 2010

J-STAGE
14

Order effect of base excision processes to repair clustered DNA damage. [in Japanese]

SHIRAISHI Iyo , SHIINA Takuya , SUGAYA Yuki , SHIKAZONO Naoya , YOKOYA Akinari

In a living cell, a multiply damaged site consisting of SSBs, base lesions and AP sites is thought to be repaired by several different repair pathways simultaneously or sequentially. Under this situat …

The Japan Radiation Research Society Annual Meeting Abstracts 2010(0), 213-213, 2010

J-STAGE
15

Dependence of the yields of AP sites and AP clusters produced in pUC18 plasmid DNA on scavenging capacity and radiation quality [in Japanese]

SHIINA Takuya , SUGAYA Yuki , SHIRAISHI Iyo , WATANABE Ritsuko , YOKOYA Akinari , TURUOKA Chizuru , SUZUKI Masao

Dependence of the yields of AP sites and AP clusters produced in pUC18 plasmid DNA on scavenging capacity and radiation qualityThe object of this study is to reveal whether the induction process of an …

The Japan Radiation Research Society Annual Meeting Abstracts 2010(0), 201-201, 2010

J-STAGE
16

Biological consequences of clustered DNA damage [in Japanese]

鹿園直哉

Notes on basic science 16(2), 14-17, 2009-03
17

Characterization of clustered DNA damage-induced mutations in <i>Escherichia coli</i>.

SHIKAZONO Naoya , NOGUCHI Miho , URUSHIBARA Ayumi , O'NEILL Peter , YOKOYA Akinari

Clustered DNA damage, defined as two or more lesions within one to two helical turns of DNA by a single radiation track, is a unique feature of ionizing radiation. We are currently focusing on the bio …

The Japan Radiation Research Society Annual Meeting Abstracts 2009(0), 108-108, 2009

J-STAGE
18

A new understanding for DNA damaging as the early process of radiobiological effect

TERATO Hiroaki , WADA Seiichi

Radiobiological effect is a complex multistep-event containing the physical, chemical and biological sub-steps. Among the sub-steps, DNA damaging (between chemical and biological steps) is the most im …

The Japan Radiation Research Society Annual Meeting Abstracts 2009(0), 70-70, 2009

J-STAGE
19

Characteristics of Clustered DNA Damage Specifically Induced by Heavy Ion Beams

SHIMAZAKI-TOKUYAMA Yuka , HIRAYAMA Ryoichi , FURUSAWA Yoshiya , IDE Hiroshi , TERATO Hiroaki

The higher biological effect of the ionizing radiation suggests some specific character of damage induced by them. When ionizing radiation passes cell as a beam, it might produce multiple lesions gath …

The Japan Radiation Research Society Annual Meeting Abstracts 2009(0), 70-70, 2009

J-STAGE Ichushi Web
20

Processing of clustered DNA damage with lesions on the same DNA strand

NOGUCHI Miho , URUSHIBARA Ayumi , YOKOYA Akinari , SHIKAZONO Naoya

Clustered DNA damage is defined as two or more lesions generated within 1-2 helical turns (10-20bp) of DNA. Ionizing radiation has a characteristic to deposit energy to local area on DNA and to induce …

The Japan Radiation Research Society Annual Meeting Abstracts 2009(0), 109-109, 2009

J-STAGE Ichushi Web

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