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  • 5-Azacytidine-induced Apoptosis in Lymphoid and Hematopoietic Organs of Adult Mice

    HOSSAIN Md. Mokbul , NAKAYAMA Hiroyuki , SHINOZUKA Junko , KATAYAMA Kei-ichi , SUZUKI Kazuhiko , DOI Kunio

    … The present study deals with the effects of 5-azacytidine (5AzC) on the lymphoid and hematopoietic tissues in adult mice. … Seven-week-old, male BALB/c mice were injected with 5AzC (100 mg/kg) intraperitoneally, and the thymus, spleen, and bone marrow were examined for cellular proliferative activity and apoptotic changes. …

    Journal of Toxicologic Pathology 13(4), 231-236, 2000-12-20

    J-STAGE  Ichushi Web  References (16) Cited by (1)

  • 5-Azacytidine-induced Apoptosis in the Central Nervous System of Developing Rat Fetuses

    LU Dong-ping , NAKAYAMA Hiroyuki , SHINOZUKA Junko , UETSUKA Koji , TAKI Ryuichi , DOI Kunio

    … with 5-azacytidine (5AzC) at 11 day of gestation. … Injection with doses less than 5 mg/kg of 5AzC killed only a few fetuses, though neuronal apoptosis was detected in most of living fetuses. … All fetuses were dead when their dams were injected with 5AzC at 9 or 10 day of gestation, whereas most of the fetuses were alive when injected after day 12. …

    Journal of Toxicologic Pathology 11(2), 133-136, 1998-06-01

    J-STAGE  Ichushi Web  References (7) Cited by (3)

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