Search Results 1-20 of 46140

Kanno Takashi , Adachi Yoshiyuki , Ohashi-Doi Katsuyo , Matsuhara Hiroki , Hiratsuka Rie , Ishibashi Ken-ichi , Yamanaka Daisuke , Ohno Naohito

… Latent BG in JCP can act as an adjuvant to induce JCP-specific antibody production via dectin-1.</p> …

Allergology International 70(1), 105-113, 2021

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Kume Yohei , Sakuma Hiroko , Sekine Hitomi , Sumikoshi Makoto , Sugimura Yoshihisa , Hosoya Mitsuaki

… Recently, anti-rabphilin-3A antibody has been reported as a potential diagnostic marker for LINH in adults; … Here, we present a case of childhood-onset LINH in a 10-yr-old boy identified as anti-rabphilin-3A antibody positive during chronic phase, 9 yr post-onset of central diabetes insipidus (CDI). … Our case study suggests that anti-rabphilin-3A antibody may be considered as a useful diagnostic marker for LINH in children.</p> …

Clinical Pediatric Endocrinology 30(1), 65-69, 2021

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Yamashita Rika , Shimizu Mikito , Baba Kousuke , Beck Goichi , Kinoshita Makoto , Okuno Tatsusada , Higuchi Osamu , Mochizuki Hideki

… Our detailed clinical, laboratory, and therapeutic descriptions highlight its unique characteristics of anti-MuSK-antibody positive MG accompanied by anti-Lrp4 and anti-titin antibodies. …

Internal Medicine 60(1), 137-140, 2021

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Koide Hiroyuki

… Thus, antibody drugs have increased in the recent two decades for disease therapy, such as cancer. …

Biological and Pharmaceutical Bulletin 44(1), 1-6, 2021

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Saito Kaku , Kaneko Reina , Kamio Takahiro , Kamiyama Emi , Muto Ryo , Sugihara Masahiro

… <p>Antibody-drug conjugates (ADCs) combine the specific antibody and cytotoxic agent by a linker and represent a promising drug class with a wider therapeutic window than conventional chemotherapeutic agents by substantiating efficient and specific drug delivery to antigen-expressing tumor cells. …

Folia Pharmacologica Japonica 156(1), 47-51, 2021

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Shimogori Hiroaki

… A definitive diagnosis of mumps was obtained in 8 patients, based on the detection of mumps-specific IgM antibody in the blood. … There were no significant differences in the peripheral blood white blood cell count, serum CRP level, or antibody index between the patients with and without complications. …

Practica Oto-Rhino-Laryngologica 114(1), 65-69, 2021

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Murakami Shuji , Usui Ryou , Nakahara Yoshiro , Kondo Tetsuro , Kato Terufumi , Saito Haruhiro

… with an anti-programmed cell death 1 (anti-PD-1) antibody may ultimately have detrimental effects. … We present the case of a patient with advanced non-small-cell lung cancer who developed active tuberculosis (TB) after initial treatment with pembrolizumab, an anti-PD-1 antibody. … Checkpoint inhibitor-related pneumonitis (CIP) is first suspected when a pulmonary shadow presents during treatment with an anti-PD-1 antibody. …

Internal Medicine, 2021

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M.D. Oagawa Satoko , M.D. Ph.D. Uchida Yuto , M.D. Kobayashi Shin , M.D. Ph.D. Takada Koji , M.D. Ph.D. Terada Kiyohito , M.D. Ph.D. Matsukawa Noriyuki

… Acute limbic encephalitis that occurred in a healthy middle-aged woman may be antibody-mediated encephalitis, requiring immediate immunotherapies. …

Rinsho Shinkeigaku, 2021

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Takahashi Fumihiko , Sawada Jun , Minoshima Akiho , Sakamoto Naka , Ono Toshiyuki , Akasaka Kazumi , Takei Hidehiro , Nishino Ichizo , Hasebe Naoyuki

Internal Medicine, 2021

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Tomoda Yuki , Okauchi Yukiyoshi , Deguchi Arichika , Takenoshita Yu , Iwahashi Hiromi , Mineo Ikuo

<p>We report the case of a 52-year-old woman with Prader-Willi syndrome (PWS) and diabetes. Her diabetes was managed with sulfonylurea followed by premixed insulin; however, her glycemic control …

Internal Medicine, 2021

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