Search Results 1-20 of 3484

  • Chromoendoscopy for Dysplasia Surveillance in Inflammatory Bowel Disease  [in Japanese]

    Flynn Ann D. , Valentine John F.

    Inflammatory bowel diseases : highlights from the official journal of the Crohn's & Colitis Foundation of America, Inc 10(1), 14-28, 2019-02

  • Treatment of Inflammatory Bowel Disease in the Older Patient  [in Japanese]

    Dorreen Alastair , Heisler Courtney , Jones Jennifer

    Inflammatory bowel diseases : highlights from the official journal of the Crohn's & Colitis Foundation of America, Inc 10(1), 2-13, 2019-02

  • Carcinogenesis of inflammatory bowel disease and surveillance  [in Japanese]

    米沢 麻利亜 , 村杉 瞬 , 伊藤 亜由美 , 大森 鉄平 , 山本 智子 , 板橋 道朗 , 中村 真一 , 長嶋 洋治 , 徳重 克年

    消化器・肝臓内科 = Gastroenterology & hepatology 5(2), 232-238, 2019-02

  • Crohn's Disease with Generalized Pustulosis Occurring After Adalimumab Administration  [in Japanese]

    南原 優希奈 , 鳥居 秀嗣

    皮膚科の臨床 61(2), 198-201, 2019-02

  • Inflammatory bowel disease and pulmonary manifestations  [in Japanese]

    藤城 泰麿 , 坂東 政司

    呼吸器内科 = Respiratory medicine 35(2), 177-183, 2019-02

  • A CASE OF ANAL FISTULA CANCER WITH INVASION TO THE PROSTATE THAT DEVELOPED 18 YEARS AFTER THE ONSET OF CROHN'S DISEASE  [in Japanese]

    村瀬 佑介 , 松橋 延壽 , 高橋 孝夫 , 田中 善宏 , 山口 和也 , 吉田 和弘

    日本臨床外科学会雑誌 80(1), 108-114, 2019

  • Clinical and Genetic Aspects of Behçet's Disease in Japan

    Kirino Yohei , Nakajima Hideaki

    … <p>Patients with Behçet's disease (BD) suffer from episodic ocular and mucocutaneous attacks, resulting in a reduced quality of life. … Mechanisms discovered by genome-wide association studies include <i>ERAP1</i>-mediated HLA class I antigen bounding pathway, autoinflammation, Th17 cells, natural killer cells, and polarized macrophages, a similar genetic architecture to Crohn's disease, ankylosing spondylitis, and psoriasis. …

    Internal Medicine 58(9), 1199-1207, 2019

    J-STAGE

  • Correlation of the endoscopic findings for small and large bowels in pediatric patients with established Crohn's disease

    Okuhira Takeru , Yoden Atsushi , Aomatsu Tomoki , Akamatsu Masano , Inoue Keisuke , Kaji Emiri , Takitani Kimitaka , Tamai Hiroshi

    … <p>Small bowel capsule endoscopy can detect subtle mucosal lesions in pediatric patients with Crohn's disease, and our aim was to evaluate its application in established ileocolonic Crohn's disease. … Colonic inflammation was evaluated with the colonic Simple Endoscopic Score for Crohn's Disease (SES-CD) (excluding the score of the terminal ileum). …

    Journal of Clinical Biochemistry and Nutrition 64(3), 257-264, 2019

    J-STAGE

  • Rebuilding of the Life of Middle-Aged Pre-Adolescence-Onset Crohn's Disease Patients  [in Japanese]

    Yamamoto Koji , Nakamura Mitsue

    <p> 本研究の目的は,青年期以前に発症した中年期のクローン病患者がこれまでどのように生活を再構築してきたのか,今後どのように病気とともに生活しようと考えているのかを明らかにすることである。中年期クローン病患者7名を対象とし,半構成的面接から得られたデータを質的に分析した。その結果,[再構築の契機となる経験][調子のよさを維持させる][体調コントロールの軸は自分][体調を優先させて生き …

    Journal of Japan Society of Nursing Research 42(1), 1_17-1_29, 2019

    J-STAGE

  • Usefulness of Ustekinumab for Treating a Case of Myelodysplastic Syndrome-Associated Inflammatory Bowel Disease

    Kono Masashi , Hagiwara Satoru , Watanabe Tomohiro , Nishida Naoshi , Enoki Eisuke , Inoue Hiroaki , Matsumura Itaru , Kudo Masatoshi , Sakurai Toshiharu , Okamoto Kazuki , Nagai Tomoyuki , Komeda Yoriaki , Kashida Hiroshi , Minaga Kosuke , Kamata Ken , Takenaka Mamoru

    … <p>Autoimmune diseases including inflammatory bowel disease (IBD) occur in association with myelodysplastic syndrome (MDS). …

    Internal Medicine, 2019

    J-STAGE

  • A case of Crohn's disease complicated by Guillain-Barrè syndrome during ustekinumab therapy  [in Japanese]

    FUKUSHIMA Tsuneo , MATSUSHIMA Makoto , NAKAJIMA Kouichi , NOZAWA Hiroshi , NISHINO Haruo , SUGITA Akira , KOGANEI Kazutaka , FUTATSUKI Ryou , YAMAGUCHI Shigeki , ASANO Shiori

    <p>Utekinumab投与中の活動期クローン病症例がギランバレー症候群を合併した.症例は23歳,男性.11歳で発症し,翌年,幽門狭窄で胃空腸吻合術を受けた.20歳で再燃しAdalimumabを開始したが,二次無効になった.2017年6月からUstekinumabを開始した.翌年6月,食欲不振,両下肢の脱力,しびれが出現し,ギランバレー症候群と診断され,immunoglobulin大 …

    Nippon Shokakibyo Gakkai Zasshi 116(4), 324-329, 2019

    J-STAGE

  • Crohn's Disease Accompanied with Small Intestinal Extramedullary Plasmacytoma

    Hanawa Yoshinori , Sugihara Nao , Furuhashi Hirotaka , Takajo Takeshi , Shirakabe Kazuhiko , Watanabe Chikako , Tomita Kengo , Komoto Shunsuke , Nagao Shigeaki , Miura Soichiro , Hokari Ryota , Higashiyama Masaaki , Shimazaki Hideyuki , Takeuchi Kengo , Ueno Hideki , Horiuchi Kazuki , Ayaki Kana , Ito Suguru , Mizoguchi Akinori , Nishii Shin , Wada Akinori , Inaba Kenichi

    … <p>We herein present the case of an immunocompetent 63-year-old man who had previously undergone resection of Crohn's disease (CD)-related small intestinal obstruction more than 30 years ago. …

    Internal Medicine, 2019

    J-STAGE

  • Food-specific IgG Antibodies in Crohn's Disease: What Came First, the Chicken or the Egg?

    Fedor Istvan , Zold Eva , Barta Zsolt

    Internal Medicine, 2019

    J-STAGE

  • Adalimumab for Crohn's disease. Monotherapy or combination therapy? -Discussion with results from DIAMOND study-  [in Japanese]

    HISAMATSU Tadakazu , SAITO Daisuke , OZAKI Ryo

    <p>クローン病治療における抗TNFα抗体製剤とチオプリン製剤の併用の可否については,有益性,副作用リスクの観点から議論が続いている.本邦において,生物学的製剤ナイーブクローン病患者における抗TNFα抗体製剤アダリムマブ(ADA)とアザチオプリン(AZA)の併用療法と,ADA単独療法の多施設共同ランダム化比較試験(DIAMOND試験)が行われた.本稿ではこのDIAMOND試験を中心に, …

    Nippon Shokakibyo Gakkai Zasshi 116(3), 193-199, 2019

    J-STAGE

  • Ustekinumab for the treatment of Crohn's disease -Indication of Ustekinumab according to efficacy and safety-  [in Japanese]

    ISHIHARA Shunji , KAWASHIMA Kousaku , KINOSHITA Yoshikazu

    <p>ウステキヌマブ(UST)はIL-12/23経路を抑制する抗炎症性の生物学的製剤である.クローン病(CD)においては,UNITI試験において本剤による寛解導入と寛解維持効果が確認され,現在本邦でも使用可能となっている.現時点では,抗TNFα抗体製剤に対する一次・二次無効症例あるいは不耐症例への使用が基本となるが,CD治療におけるUSTの位置付けについては,さらなるreal-worl …

    Nippon Shokakibyo Gakkai Zasshi 116(3), 216-223, 2019

    J-STAGE

  • Crohn's Disease with Mesalazine Allergy that Was Difficult to Differentiate from Comorbid Ulcerative Colitis

    Tsuboi Rumiko , Matsumoto Satohiro , Miyatani Hiroyuki , Mashima Hirosato

    … <p>An 18-year-old man diagnosed with ileocolonic Crohn's disease with circumferential strictures of the ascending colon started treatment with mesalazine and subsequently underwent right hemicolectomy. … In patients of inflammatory bowel disease receiving mesalazine with an atypical clinical course, the possibility of mesalazine allergy must be borne in mind. …

    Internal Medicine 58(5), 649-654, 2019

    J-STAGE

  • Elemental Diet Regulates Intestinal Permeability and Antibody Production in Indomethacin-Induced Intestinal Injury Rats

    KIKUCHI Yuko , MATSUO Mariko , NABETA Chiaki , AKAHOSHI Asuka , MINAMI Hisanori

    … <p>Crohn's disease is a type of inflammatory bowel disease of unknown etiology. … Administration of indomethacin (Indo) to rats induces acute mucosal lesions similar to those observed in Crohn's disease patients, but the damage can be prevented by feeding the animals an elemental diet (ED). …

    Journal of Nutritional Science and Vitaminology 65(1), 31-37, 2019

    J-STAGE

  • Adrenomedullin: A Novel Therapy for Intractable Crohn's Disease with a Loss of Response to Infliximab

    Ashizuka Shinya , Kuroishi Nobuko , Nakashima Koji , Inatsu Haruhiko , Kita Toshihiro , Kitamura Kazuo

    … <p>A 35-year-old man with refractory Crohn's disease showed a loss of response to infliximab after requiring treatment with infliximab at 10 mg/kg together with steroid to maintain remission. … Adrenomedullin promoted mucosal healing and led to the re-induction of remission in Crohn's disease in a patient with a loss of response to infliximab. …

    Internal Medicine, 2019

    J-STAGE

  • Atypical Clinical Presentation of Crohn's Disease with Superior Mesenteric Vein Obstruction and Protein-losing Enteropathy

    Ito Suguru , Sugihara Nao , Hanawa Yoshinori , Furuhashi Hirotaka , Takajo Takeshi , Shirakabe Kazuhiko , Watanabe Chikako , Komoto Shunsuke , Tomita Kengo , Nagao Shigeaki , Shinozaki Masami , Higashiyama Masaaki , Nakagawa Akihiko , Kubota Michio , Miyagishima Daisuke , Gotoh Nobuaki , Miura Soichiro , Ueno Hideki , Hokari Ryota , Horiuchi Kazuki , Mizoguchi Akinori , Soga Shigeyoshi , Tanemoto Rina , Nishii Shin , Terada Hisato , Wada Akinori

    … <p>We herein report a 44-year-old man suffering from systemic edema due to protein-losing enteropathy (PLE) with superior mesenteric vein (SMV) obstruction and development of collateral veins, which subsequently proved to be a chronic result of thrombosis and a complication of Crohn's disease (CD). …

    Internal Medicine 58(3), 369-374, 2019

    J-STAGE

  • Late-Onset Anastomotic Leakage with Bleeding in Systemic AA Amyloidosis Complicating Crohn's Disease  [in Japanese]

    Touge Ryo , Shimada Norimitsu , Ohge Hiroki , Okamoto Nobuyuki , Yano Raita , Watadani Yusuke , Uemura Kenichiro , Murakami Yoshiaki , Sueda Taijiro

    <p>続発性アミロイドーシスを合併したクローン病に対し外科的治療を行い,非典型的な合併症を経験したので報告する.症例は36歳の男性で,瘻孔形成状態で15年間内科的治療が行われていたが症状増悪あり,加療目的に紹介となった.入院後に進行性の腎機能障害を認め,腎生検にて腎アミロイドーシスの診断となり血液透析が導入された.消化管には回腸・直腸の狭窄病変あり回盲部切除術・人工肛門造設術,高位前方 …

    The Japanese Journal of Gastroenterological Surgery 52(1), 53-59, 2019

    J-STAGE

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