Search Results 1-20 of 113

  • MEG–BMI to Control Phantom Limb Pain

    YANAGISAWA Takufumi , KAMITANI Yukiyasu , SAITOH Youichi , FUKUMA Ryohei , SEYMOUR Ben , HOSOMI Koichi , KISHIMA Haruhiko , SHIMIZU Takeshi , YOKOI Hiroshi , HIRATA Masayuki , YOSHIMINE Toshiki

    … <p>A brachial plexus root avulsion (BPRA) causes intractable pain in the insensible affected hands. … Such pain is partly due to phantom limb pain, which is neuropathic pain occurring after the amputation of a limb and partial or complete deafferentation. … Previous studies suggested that the pain was attributable to maladaptive plasticity of the sensorimotor cortex. …

    Neurologia medico-chirurgica 58(8), 327-333, 2018

    J-STAGE  Ichushi Web 

  • MEG–BMI to Control Phantom Limb Pain

    YANAGISAWA Takufumi , KAMITANI Yukiyasu , SAITOH Youichi , FUKUMA Ryohei , SEYMOUR Ben , HOSOMI Koichi , KISHIMA Haruhiko , SHIMIZU Takeshi , YOKOI Hiroshi , HIRATA Masayuki , YOSHIMINE Toshiki

    … <p>A brachial plexus root avulsion (BPRA) causes intractable pain in the insensible affected hands. … Such pain is partly due to phantom limb pain, which is neuropathic pain occurring after the amputation of a limb and partial or complete deafferentation. … Previous studies suggested that the pain was attributable to maladaptive plasticity of the sensorimotor cortex. …

    Neurologia medico-chirurgica, 2018

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  • Induction of cortical plasticity reveals the mechanism of the phantom limb pain and develops novel treatment  [in Japanese]

    Yanagisawa Takufumi , Kamitani Yukiyasu , Saitoh Yoichi , Fukuma Ryohei , Ben Seymour , Hosomi Koichi , Shimizu Takeshi , Kishima Haruhiko , Hirata Masayuki , Yokoi Hiroshi , Yoshimine Toshiki

    … Phantom limb pain is neuropathic pain after amputation of a limb and partial or complete deafferentation such as brachial plexus root avulsion. … The underlying cause of this pain has been attributed to maladaptive plasticity of the sensorimotor cortex. … It has been suggested that experimental reorganization would affect pain. …

    PAIN RESEARCH 33(1), 26-31, 2018

    J-STAGE  Ichushi Web 

  • Subarachnoid Block-Induced Deafferentation Pain Successfully Treated with Pentazocine

    Kishikawa Hiroaki , Wajima Zen'ichiro , Shitara Toshiro , Shimizu Toru , Adachi Hitoshi , Sakamoto Atsuhiro

    … <p>Deafferentation pain induced by subarachnoid block (SAB) is rare, but it can appear in the form of recurrent phantom lower limb pain, new acute-onset stump pain in amputees, lower limb pain in patients with tabes dorsalis, and neuropathic pain. …

    Journal of Nippon Medical School 84(4), 183-185, 2017

    J-STAGE  Ichushi Web 

  • Induced sensorimotor brain plasticity controls pain in phantom limb patients

    Yanagisawa Takufumi , Fukuma Ryohei , Seymour Ben , Hosomi Koichi , Kishima Haruhiko , Shimizu Takeshi , Yokoi Hiroshi , Hirata Masayuki , Yoshimine Toshiki , Kamitani Yukiyasu , Saitoh Youichi

    … The cause of pain in a phantom limb after partial or complete deafferentation is an important problem. … A popular but increasingly controversial theory is that it results from maladaptive reorganization of the sensorimotor cortex, suggesting that experimental induction of further reorganization should affect the pain, especially if it results in functional restoration. …

    Nature Communications (7), 2016-10-27

    IR 

  • 1P2-L04 Development of VR rehabilitation system for phantom limb pain with high therapeutic effect and usability  [in Japanese]

    ICHINOSE Akimichi , SANO Yuko , WAKE Naoki , OSUMI Michihiro , SUMITANI Masahiko , KUMAGAYA Shin-ichiro , KUNIYOSHI Yasuo

    … Most of the patients who experienced a limb amputation or deafferentation suffer from phantom limb pain. … Phantom limb pain is a refractory pain, and there are few effective treatments since the pathogenesis is unknown. … Rehabilitation using virtual reality (VR) is promising as a new treatment for phantom limb pain. …

    The Proceedings of JSME annual Conference on Robotics and Mechatronics (Robomec) 2015(0), _1P2-L04_1-_1P2-L04_4, 2015

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  • Activation of microglia in the nucleus of the solitary tract by inferior alveolar nerve injury

    Kakihara Rina , Suwabe Takeshi , Nishikawa Yasuo , Morita Shosuke

    Deafferentation of somatosensory trigeminal nerves innervating dental pulp and periodontal tissue results in a higher taste threshold persisting for a long time in humans. … Peripheral injury to the inferior alveolar nerve (IAN), one of the dental nerves, leads to glial responses predominantly in the trigeminal spinal subnucleus caudalis and spinal dorsal horn, and abnormal pain sensation via a mechanism involving the active microglia. …

    Journal of Osaka Dental University 49(1), 21-26, 2015

    J-STAGE  Ichushi Web 

  • Hypnosis for Phantom Limb Pain After a Root Avulsion Injury of Brachial Plexus  [in Japanese]

    水谷 みゆき

    臨床催眠学 = Japanese journal of clinical hypnosis 15, 6-17, 2014-03

    Ichushi Web 

  • A Memoir of My Research on Pain and Analgesia for 39 Years  [in Japanese]

    Kuraishi Yasushi

    …   This review describes my research for the past 39 years regarding the pharmacology of pain and analgesia. … We developed an animal model of cancer pain using melanoma cells. … We have shown that the suppression of cancer pain results in the inhibition of tumor growth and lung metastasis, and that melanoma cells release several algogenic substances including ATP, endothelin-1, and bradykinin. …

    YAKUGAKU ZASSHI 134(11), 1125-1142, 2014

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  • The Changes of c-Fos Expression by Motor Cortex Stimulation in the Deafferentation Pain Model

    KUDO Kanae , TAKAHASHI Toshio , SUZUKI Shigeharu

    … The effect of motor cortex stimulation (MCS) therapy for deafferentation pain was evaluated based on c-Fos, a known pain marker. … Cats were divided into three groups: a deafferentation pain group in which the left trigeminal ganglion was destroyed, an MCS group in which MCS was used following destruction of the trigeminal ganglion, and a control group. …

    Neurologia medico-chirurgica 54(7), 537-544, 2014

    J-STAGE  Ichushi Web 

  • Three cases of anesthesia dolorosa after surgery or nerve block for trigeminal neuralgia  [in Japanese]

    WAKAIZUMI Kenta , HIDA Kumiko , YONEKAWA Yuko , TOYOKAWA Hideki , KAMIJIMA Kenya , ABE Yoichiro

    … Case 1: A 71-year-old woman complained of severe pain with sensory loss in the right side of her face for 2 years after balloon compression of the Gasserian ganglion for TN. … She did not respond to any medication, but finally achieved pain relief with amitriptyline (45 mg). … In this patient, amitriptyline (30 mg) provided pain relief. …

    Journal of Japan Society of Pain Clinicians 21(1), 31-34, 2014

    J-STAGE  Ichushi Web 

  • Electroconvulsive therapy for deafferentation pain and morphine tolerance  [in Japanese]

    土井 永史 , 米良 仁志 , 鮫島 達夫 [他]

    臨床精神医学 42(4), 433-442, 2013-04

    Ichushi Web 

  • Cerebrospinal Stimulation and Low-dose Ketamine Drip Infusion Therapy for the Treatment of Neuropathic Pain  [in Japanese]

    YAMAMOTO Takamitsu , SUMI Koichiro , OBUCHI Toshiki , OTAKA Minoru , KANO Toshikazu , KOBAYASHI Kazutaka , OSHIMA Hideki , FUKAYA Chikashi , KATAYAMA Yoichi

    … For the treatment of intractable neuropathic pain, drug challenge test is necessary and useful to examine the pharmacological background of the pain in each case. … For the treatment of peripheral deafferentation pain, which includes phantom limb pain and peripheral nerve injury pain, deep brain stimulation therapy of the thalamic relay nucleus is suitable. …

    Journal of Nihon University Medical Association 69(3), 176-182, 2010-06-01

    J-STAGE  Ichushi Web  References (21)

  • A case report of spinal cord tumor with paroxysmal pain in occiput and neck during night  [in Japanese]

    森 一越 , 鈴木 繁 , 川村 研 [他]

    Japanese journal of pediatrics 62(7), 1679-1684, 2009-07

    Ichushi Web 

  • The mechanism of high-frequency rTMS for intractable pain, a TMS study  [in Japanese]

    HOSOMI Koichi , SAITOH Youichi , KISHIMA Haruhiko , HIRATA Masayuki , OSHINO Satoru , TANI Naoki , GOTO Tetsu , YANAGISAWA Takufumi , ALI Mohamed , YOSHIMINE Toshiki

    Pain research : the journal of the Japanese Society for the Study of Pain = 日本疼痛学会誌 24(1), 23-29, 2009-02-28

    Ichushi Web  References (19)

  • <b>Functional mapping in motor cortex of the patients </b><b>with phantom limb pain </b>  [in Japanese]

    Yanagisawa Takufumi , Saitoh Youichi , Hosomi Koichi , Hirata Masayuki , Kishima Haruhiko , Oshino Satoru , Goto Tetsu , Yoshimine Toshiki

    …  In this study, TMS was applied for functional mapping of the motor cortex in patients with deafferentation pain. … We studied 7 patients with intractable deafferentation pain (phantom limb: 3, brachial plexus avulsion: 4) and 2 patients with spinal cord injury without pain. …

    PAIN RESEARCH 24(1), 31-36, 2009

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  • <b>The mechanism of high-frequency rTMS </b><b>for intractable pain, a TMS study </b>  [in Japanese]

    Hosomi Koichi , Yoshimine Toshiki , Saitoh Youichi , Kishima Haruhiko , Hirata Masayuki , Oshino Satoru , Tani Naoki , Goto Tetsu , Yanagisawa Takufumi , Ali Mohamed

    …  We have previously reported the efficacy of navigation-guided 5-Hz repetitive transcranial magnetic stimulation (rTMS) of the primary motor cortex in relief of intractable neuropathic pain. … The objective of this study was to assess changes of cortical excitability induced by rTMS which might give an insight to the mechanism of pain relief with rTMS. …

    PAIN RESEARCH 24(1), 23-29, 2009

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  • Repetitive transcranial magnetic stimulation for neuropathic pain  [in Japanese]

    HOSOMI Koichi , SAITOH Youichi , KISHIMA Haruhiko , TANI Naoki , HIRAYAMA Azuma , SHIMOKAWA Toshio , OSHINO Satoru , HIRATA Masayuki , YOSHIMINE Toshiki

    Functional neurosurgery : proceedings of the annual meeting of the Japan Society for Stereotactic and Functional Neurosurgery 47(2), 135-140, 2008-12-25

    Ichushi Web  References (18)

  • Mechanism of Pain Relief with Spinal Cord Stimulation and Motor Cortex Stimulation for Intractable Neuropathic Pain : PET Analysis  [in Japanese]

    KISHIMA Haruhiko , SAITOH Youichi , HIRAYAMA Azuma , HIRATA Masayuki , OSHINO Satoru , TANI Naoki , HOSOMI Koichi , KATO Amami , YOSHIMINE Toshiki

    CI研究 : progress in computed imaging 29(3), 153-158, 2008-03-31

    Ichushi Web  References (13)

  • Mechanistic analysis of motor cortex stimulation for phantom limb pain  [in Japanese]

    YANAGISAWA Takufumi , SAITOH Youichi , HIRATA Masayuki , YAMASHITA Okito , KAMITANI Yukiyasu , OSHINO Satoru , KISHIMA Haruhiko , TANI Naoki , HOSOMI Kouichi , GOTO Tetsu , SATOU Masaaki , KAKIGI Ryusuke , YOSHIMINE Toshiki

    …  Phantom limb pain and other deafferentation pain are characterized by changes in cortical processing and organization (cortical reorganization), poor response to conventional treatments. … Whereas several studies reported a close relationship between imagery movements of the amputated or paralyzed limb and the intractable pain, the alterations in the motor cortex related to the imagery movements has not yet been explored in detail. …

    PAIN RESEARCH 23(1), 27-34, 2008-01-31

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