Tabuchi Maiko
,
Minami Hitomi
,
Akazawa Yuko
,
Ashida Miwa
,
Hara Toshihide
,
Ichinose Kunihiro
,
Kitayama Moto
,
Hashiguchi Keiichi
,
Matsushima Kayoko
,
Yamaguchi Naoyuki
,
Takeshima Fuminao
,
Kondo Hisayoshi
,
Kawakami Atsushi
,
Nakao Kazuhiko
… Although the baseline esophago-gastroduodenoscopy examination did not show severe erosion in the majority of patients,the mean total FSSG score before vonoprazan treatment was notably high (25.2±10.7) compared to a normal score of <8. … The mean improvement rate of the total FSSG, acid reflux and dysmotility scores were 60.8±21.2% (P=0.0004), 67.3±24.8% (P<0.0001) and 55.4±26.0% (P=0.0022), respectively.These results suggest that vonoprazan may be a potentially effective treatment for GERD in patients with SSc. …
IR