Search Results 1-20 of 1442

  • Is cell block technique useful to predict histological type in patients with ovarian mass and/or body cavity fluids?

    Maseki Zenta , Kajiyama Hiroaki , Nishikawa Eri , Satake Tatsunari , Misawa Toshiya , Kikkawa Fumitaka

    … Between 2008 and 2017, 15 peritoneal or pleural fluid samples obtained from patients with ovarian or peritoneal carcinoma or other gastrointestinal malignancies were preoperatively subjected to a diagnostic evaluation to predict the histological type and original organ. …

    Nagoya Journal of Medical Science 82(2), 225-235, 2020-05

    IR  DOI 

  • Elastic and Collagen Fibers Segmentation Based on U-Net Deep Learning Using Hematoxylin and Eosin Stained Hyperspectral Images (Special Issue on Extended Papers Presented in IEVC2019)

    SEPTIANA Lina , SUZUKI Hiroyuki , ISHIKAWA Masahiro , OBI Takashi , KOBAYASHI Naoki , OHYAMA Nagaaki , ICHIMURA Takaya , SASAKI Atsushi , WIHARDJO Erning , ARJADI Harry

    IIEEJ transactions on image electronics and visual computing 8(1), 17-26, 2020

  • Potentiation of developmental malformation and neurotoxicity of neonicotinoid insecticide, Acetamiprid  [in Japanese]

    LEE Christine Li Mei , MATSUFUSA Rie , TIONG Thomas Kwong Soon , LOPEZ Johnny Ademir , NOMURA Yoko , KANDA Yasunari , YOSHIDA Sachiko

    <p> ネオニコチノイドは、高い浸透性と昆虫駆除効率を有する新しいクラスの殺虫剤で、ニコチンの化学構造を模倣し、ニコチン性アセチルコリン受容体(nAChR)に結合して殺虫効果をもたらす。昆虫と哺乳類ではnAChRの感受性が異なるため、ネオニコチノイドは安全な殺虫剤と考えられてきたが、近年その安全性に疑問を呈する報告がなされている。本研究では、代表的なネオニコチノイドの一種であるアセタミ …

    Annual Meeting of the Japanese Society of Toxicology 47.1(0), P-6S, 2020


  • Relationship between blood erythropoietin and renal erythropoietin induction in rats exposed to cadmium  [in Japanese]

    HORIGUCHI Hyogo , OGUMA Etsuko , YASUOKA Yukiko , OMORI Yuki , KAWAHARA Katsumasa , NONOGUCHI Hiroshi

    … We observed levels of blood EPO and renal EPO induction in rats exposed to Cd and investigated the relationship between them to clarify the kinetics of EPO in Cd toxicity. … After that, peripheral blood and kidneys were taken. …

    Annual Meeting of the Japanese Society of Toxicology 47.1(0), P-113, 2020


  • Morphological and Functional Changes in Skin of Adult Male Rats Chronically Treated with Letrozole, a Nonsteroidal Inhibitor of Cytochrome P450 Aromatase

    Misiakiewicz-Has Kamila , Zawiślak Alicja , Pilutin Anna , Kolasa-Wołosiuk Agnieszka , Szumilas Paweł , Duchnik Ewa , Wiszniewska Barbara

    … <p>Skin is a target for hormones and a site of hormone production. … The aim of the study was to investigate the morphology of the dermis and immunoexpression of androgen receptor (AR), estrogen receptor α and β (ERα, ERβ), luteinizing hormone receptor (LHR), follicle-stimulating hormone receptor (FSHR), and cytochrome P450 aromatase (P450arom) in male rats with a deficit of estradiol. …



  • Demonstration of Deoxyribonucleic Acid in Colorectal Cancer Using Feulgen reaction

    Salih Magdi M. , Elesawy Basem , Al-Ayli Salman M. , Al-Otaibi Awad A. , Al-Thobiti Fares M. , Almehmadi Mazen

    … Cells derived from many human malignant tissues have altered chromatin content and structure. … To demonstrate DNA in colorectal cancer cells using Feulgen reaction, and to determine the association between colon cancer grade and cellular DNA content.</p><p><b>Design:</b> … Taif city- King Abdul Aziz specialized hospital.</p><p><b>Patients and methods:</b> …

    Annals of Cancer Research and Therapy 28(2), 88-92, 2020


  • Lipid Core Plaque Distribution Using Near-infrared Spectroscopy Is Consistent with Pathological Evaluation in Carotid Artery Plaques

    KOTSUGI Masashi , PARK Young-Soo , NAKASE Hiroyuki , NAKAGAWA Ichiro , HATAKEYAMA Kinta , PARK HunSoo , SATO Fumiya , FURUTA Takanori , NISHIMURA Fumihiko , YAMADA Shuichi , MOTOYAMA Yasushi

    … However, lipid-rich plaques cause embolic complications and sequelae. … Near-infrared spectroscopy (NIRS) can identify lipid components by applying a near-infrared absorption pattern, and the distribution of lipid components can be evaluated as the maximum lipid core burden index (maxLCBI). … Intravascular ultrasound (IVUS) equipped with NIRS has been clinically applied recently, and its diagnostic usefulness and validation have been reported for coronary arteries; …

    Neurologia medico-chirurgica, 2020


  • The Effect of Thymoquinone on the Characteristics of the Brain Extracellular Space in Transient Middle Cerebral Artery Occlusion Rats

    Fan Chaoxin , Tian Fang , Zhao Xin , Sun Yi , Yang Xiaogai , Han Hongbin , Pu Xiaoping

    … <p>The extracellular space (ECS) is the space between the neurons and the capillaries in the brain. … The volume fraction (α) and the tortuosity (λ) are the main parameters used to describe its characteristics. … Thymoquinone has been proved to possess anti-oxidant and anti-inflammatory activity. …

    Biological and Pharmaceutical Bulletin 43(9), 1306-1314, 2020


  • Osthole Improves Cognitive Function of Vascular Dementia Rats: Reducing Aβ Deposition <i>via</i> Inhibition NLRP3 Inflammasome

    Liu Yiwei , Chen Xia , Gong Qihai , Shi Jingshan , Li Fei

    … <p>Vascular dementia (VD) is a common neurodegenerative disease, and the cognitive dysfunction is a major manifestation of VD. … Lots of evidences showed that beta-amyloid (Aβ) deposition and neuroinflammation act as vital elements in the progress of VD. … The previous studies showed that osthole (OST) can improve the cognitive function of VD and Alzheimer's disease (AD). …

    Biological and Pharmaceutical Bulletin 43(9), 1315-1323, 2020


  • Presence of the annular ridge and location of the coronary sinus ostium as morphological features of the right atrium and interatrial septum in healthy common marmosets (<i>Callithrix jacchus</i>)

    Suzuki Motoaki , Ogata Masaki , Murata Yuzo , Suzuki Satsuki

    … <p>To effectively use a common marmoset (<i>Callithrix jacchus</i>) as an experimental animal species, it is critical to establish a normal characteristics and morphology of the organs of the common marmoset. … Although gross morphology of the common marmoset heart is reportedly the same as that of humans, little information is available regarding detailed morphology of the right atrium and the interatrial septum. …

    Experimental Animals 69(3), 295-305, 2020


  • Use of mixture of xylean Clear-Rite<sup>TM</sup>3 as an alternative reagent and alcohol for tissue delipidation with an auto tissue processor  [in Japanese]

    YOSHIDA-TANAKA Miho , KURAOKA Kazuya , KAN Arisa , FUJISAWA Hiroki , YASUMURA Naoko , SAIKI Yumi , MIYANO Hideaki , TANIYAMA Kiyomi

    … 4)ヘマトキシリン・エオジン(Hematoxylin Eosin; …

    Japanese Journal of Medical Technology 69(3), 408-415, 2020


  • Histological investigation of picosecond laser-toning and fractional laser therapy

    Nakano Shunji

    … Background and Aims: </b> … Rejuvenation therapy using picosecond pulse laser and picosecond pulsed fractional therapy with a fractional lens have been performed with clinical effects evaluated. … In this study, influence of laser-toning and fractional therapy using picosecond pulse laser on photoaging was histologically investigated. … Subjects and Methods: </b> …

    LASER THERAPY 29(1), 53-60, 2020


  • Quantitative Visualization of Lanthanum Accumulation in Lanthanum Carbonate-Administered Human Stomach Tissues Using Mass Spectrometry Imaging

    Shimma Shuichi , Makino Yoshiki , Kojima Kazuto , Hirata Takafumi

    … Furthermore, most of these are case reports, and the relationship between the distribution of the metal and clinical observations in human samples is not well understood. … We also compared the distribution of <sup>139</sup>La in tissue and histochemical results. … In contrast, we observed a debris-like crystal morphology in hematoxylin and eosin staining tissues. …

    Mass Spectrometry 9(1), A0086-A0086, 2020


  • Photodynamic Therapy Delays Cutaneous Wound Healing in Mice

    Sun Yan , Tosa Mamiko , Takada Hiroya , Ogawa Rei

    … We examined the effectiveness and underlying mechanisms of PDT in a murine model of acute wound healing. … On Day 14, the wounds were excised and subjected to histological and immunohistochemical analysis. … On Day 14, hematoxylin and eosin (HE) staining showed a continuous epithelial lining in untreated wounds. …

    Journal of Nippon Medical School 87(3), 110-117, 2020


  • A Trial Study for Lens Capsule Regeneration Using iPS-derived Cell Aggregates  [in Japanese]

    Hiramatsu Noriko , Yamamoto Naoki

    <p><b>方法</b>:ヒト虹彩由来iPS細胞を用いて, 静置・回転浮遊培養法にて分化誘導した細胞凝集体の切片標本を作製し, HE染色, <i>α</i>A-crystalline, p75NTRの免疫染色を実施した. <b>結果</b>:凝集体の最表層には上皮様細胞が単層に配列し, <i>α< …

    The Journal of The Japanese Society for Cataract Research 32(1), 44-46, 2020


  • A case of Epstein-Barr virus-associated carcinoma with lymphoid stroma  [in Japanese]

    Sakakura Akie , Ariga Hiroyuki , Kumakura Yuri , Kashimura Junya

    … Histological findings of the biopsy specimen revealed gastric carcinoma with lymphoid stroma on hematoxylin and eosin staining, and the tumor cells were positive for the <i>in situ</i> … Enhanced computed tomography images revealed no metastasis to lymph nodes and other organs in the chest and abdomen. …

    Progress of Digestive Endoscopy 96(1), 93-94, 2020


  • A case of gastric AL amyloidosis with atypical endoscopic imaging findings  [in Japanese]

    Sumida Chihiro , Kako Makoto , Sasaki Akiko , Ichita Chikamasa , Kimura Karen , Nishino Takashi , Tazawa Tomohiko , Tasaki Junichi , Masuda Sakue , Koizumi Kazuya

    … Subsequent hematoxylin and eosin staining of sections revealed small clusters of eosinophilic non-structural substances that also tested positive for amyloids through Congo red staining. … Additional testing indicated a diagnosis of AL-type amyloidosis, revealing systemic amyloidosis in the lower gastrointestinal tract, kidneys, and bone marrow. …

    Progress of Digestive Endoscopy 96(1), 67-69, 2020



    ABE Maasa , NAKAMAKI Tsuyoshi , TAKIMOTO Masafumi , SHIOZAWA Eisuke , HATTORI Norimichi , MURAI So , HONMA Mayumi , SASAKI Yosuke , MIURA Sakiko , YAMOCHI Toshiko , TATE Genshu

    … 統および多血球系統の異形成を伴ったMDSのうち,70歳未満の患者では細胞密度が30%未満,70歳以上の患者では細胞密度が20%未満である基準を満たす症例をHypo-MDSとした.骨髄病理組織を用いたHematoxylin-eosin染色標本で組織形態を評価し,抗p53抗体,抗HbF抗体,抗CD34抗体,抗c-kit抗体, 抗CD42b抗体,抗CD4抗体,抗CD8抗体,抗CD68抗体,抗CD163抗体,抗MCT抗体,抗MCTC抗体を用いた免疫組織化学で細胞抗原 …

    Journal of The Showa University Society 80(1), 40-50, 2020

    IR  J-STAGE 

  • <i>Dendrobium officinale</i> Attenuates Myocardial Fibrosis <i>via</i> Inhibiting EMT Signaling Pathway in HFD/STZ-Induced Diabetic Mice

    Zeng Jie , Li Dongning , Li Zhubo , Zhang Jie , Zhao Xiaoyan

    … <p>Cardiac fibrosis is a major contributor for diabetic cardiomyopathy and <i>Dendrobium officinale</i> … possessed therapeutic effects on hyperglycemia and diabetic cardiomyopathy. … (DOE) from dry stem was analyzed by HPLC and phenol-sulfuric acid method. … The groups were as follows: control group, model group, DOE low, medium, high dose group (75, 150, 300 mg/kg) and Metformin positive group (125 mg/kg). …

    Biological and Pharmaceutical Bulletin 43(5), 864-872, 2020


  • Structural Analysis of Experimentally Induced Disc Herniation-Like Changes in the Rat

    Ujigo Satoshi , Jonsson Daniel , Bogestål Yalda , Håkansson Joakim , Rosendahl Jennifer , Brive Lena , Olmarker Kjell

    … However, it was recently suggested that the disc herniation mass is a product of bioactive substances from the disc and that the disc hernia would more likely be scar tissue than herniated disc material. … In this study, we aimed to analyze the structural components of experimentally induced disc herniations and compare with scar tissue and nucleus pulposus, in the rat.</p><p>Methods: Twenty-eight rats had their L4-5 discs punctured. …

    Spine Surgery and Related Research 4(2), 117-123, 2020


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