Search Results 1-20 of 1647

  • Impacts of Skeletonized Bilateral Internal Mammary Artery Bypass Grafting on the Risk of Deep Sternal Wound Infection:Insights from a Single-Center Study of Propensity Score-Matched Data

    Ji Qiang , Zhao Yun , Liu Huan , Yang Ye , Wang YuLin , Ding WenJun , Xia LiMin , Wei Lai , Wang ChunSheng

    … After matching, treatment type (skeletonized BIMA grafting versus skeletonized SIMA grafting) was not an independent risk factor for postoperative DSWI (OR = 1.309, 95% CI 0.897-2.714, <i>P</i> … Patients with skeletonized BIMA grafting received similar surgical mortality and major postoperative morbidity as did matched patients with skeletonized SIMA grafting.</p> …

    International Heart Journal, 2020


  • High Nighttime Heart Rate is Associated with Increased Risk of All-Cause Mortality in Patients with Heart Failure and Reduced Ejection Fraction

    Wang Chun-Li , Chan Yi-Hsin , Lee Hsin-Fu , Hsiao Fu-Chih , Chu Pao-Hsien

    … This study aimed to evaluate which measures of HR were associated with all-cause mortality in patients with heart failure and reduced ejection fraction (HFrEF). … We examined the associations of resting, 24 hour, and nighttime HRs with all-cause mortality. … Resting, nighttime, and 24 hour HRs were significantly associated with all-cause mortality, also after adjusting for conventional risk factors. …

    International Heart Journal, 2020


  • Post-Traumatic West Syndrome due to Abusive Head Trauma in Two Infants with Different Brain Imaging Findings

    Takeda Risa , Kobayashi Satoru , Kamioka Naomi , Hamajima Naoki , Muramatsu Kanji , Suzuki Satoshi

    … AHT is an important cause of morbidity and mortality in young children, particularly those younger than 12 months of age. … AHT may be an important risk factor for postnatal West syndrome. …

    The Tohoku Journal of Experimental Medicine 250(3), 167-171, 2020


  • Modeling Diachronic Cork Oak Dieback–Comparison of Two Case Studies

    Camilo-Alves Constanca , Saraiva-Dias Susana , Dinis Cati , Rosário Felix Maria do , Varandas Carla , Nuno de Almeida Ribeiro

    … <p>Widespread events of cork oak mortality are disturbing the system and jeopardizing cork production. … To understand the dynamics of cork oak mortality and the factors associated with it, a diachronic study was performed in two farms located in Évora, Portugal. … Mortality index and tree crown cover were calculated for each one of them. … Maps of the kernel density of tree mortality were generated to select key spots for pests and diseases field survey. …

    FORMATH, 2020


  • Ischemia-Modified Albumin Is Associated with Arterial Stiffness in Hemodialysis Patients

    Jiao Dan , Guo Feng , Yue Meng , Tian Zhen

    … <p>Increased arterial stiffness is strongly associated with cardiovascular morbidity and mortality in dialysis patients. …

    International Heart Journal, 2020


  • Health status of workers approximately 60 years of age and the risk of early death after compulsory retirement: A cohort study

    Sakurai Masaru , Nogawa Koji , Nakagawa Hideaki , Ishizaki Masao , Miura Katsuyuki , Nakashima Motoko , Morikawa Yuko , Kido Teruhiko , Naruse Yuchi , Nogawa Kazuhiro , Suwazono Yasushi

    … We investigated the association between the health status of workers approximately 60 years of age and the risk of all-cause mortality after compulsory retirement in Japan.</p><p><b>Methods</b>: The 2026 participants (1299 males and 727 females) had retired from a metal-products factory at ≥60 years of age. …

    Journal of Occupational Health 62(1), n/a, 2020


  • Advanced age is not a risk factor for mortality in patients with bacteremia caused by extended-spectrum β-lactamase-producing organisms: A multicenter cohort study

    Mitsuboshi Satoru , Tsuruma Naoki , Watanabe Kazuya , Takahashi Shigehiro , Ito Atsuko , Nakashita Manami , Suzuki Mitsuyuki , Kobayashi Kenichi , Tsugita Masami

    … Multivariate regression analysis showed that other sites of infection had a positive association with 30-day mortality (odds ratio [OR] 27.50, 95% confidence interval [CI] 2.90–260.00) and biliary tract infection tended to have a positive association with 30-day mortality (OR 8.90, 95% CI 0.88–89.90) compared with urinary tract infection. … However, age ≥85 years was not associated with 30-day mortality. …

    Japanese Journal of Infectious Diseases, 2020


  • Prognostic impact of hyperbilirubinemia in the early phase after allogeneic hematopoietic stem cell transplantation

    Omori Ikuko , Wakita Satoshi , Okamoto Muneo , Tamai Hayato , Nakayama Kazutaka , Yui Shunsuke , Inokuchi Koiti , Yamaguchi Hiroki , Hirakawa Tsuneaki , Inai Kazuki , Onai Daishi , Marumo Atsushi , Yamanaka Satoshi , Sakaguchi Masahiro , Fujiwara Yusuke

    … Elevated total bilirubin (T-Bil) level was the most frequently observed unfavorable prognostic factor, having the greatest impact on overall survival (OS), progression-free survival (PFS), and non-relapse mortality (NRM) (probability of unfavorable outcome in patients without elevated T-Bil level versus that in patients with elevated T-Bil level: OS, 58.9% vs. 15.4%, <i>p </i>< …

    Journal of Nippon Medical School, 2020


  • Influence of The Sagittal Vertical Axis on The Risk of Falls in Community-Dwelling Elderly People: A Retrospective Longitudinal Study

    Yamada Tomohiro , Ide Koichiro , Watanabe Yuh , Matsuyama Yukihiro , Yamato Yu , Hasegawa Tomohiko , Yoshida Go , Yasuda Tatsuya , Banno Tomohiro , Arima Hideyuki , Oe Shin , Ushirozako Hiroki

    … Compared with younger people, elderly people possess increased risk factors for falls, and falling among the elderly is associated with increased mortality. … P = 0.03) to be associated with the risk of falls, independent of other factors in the univariate analysis.</p><p><b>Conclusions</b>: The sagittal vertical axis was an independent risk factor for falls, and the prevalence of vertebral fractures and prone truck extension correlated with the sagittal vertical axis. …

    Spine Surgery and Related Research, 2020


  • Cardiac Function and Perioperative Management  [in Japanese]

    山浦 健

    … Heart failure (HF) is associated with postoperative mortality among patients undergoing elective non-cardiac surgery. … Not only LV systolic function but also diastolic dysfunction is reported to be an independent risk factor for adverse cardiovascular morbidities and mortalities in high-risk surgical patients including cardiovascular surgery and sepsis patients. … These are risk factor of LV diastolic dysfunction. …

    福岡醫學雜誌 110(4), 195-201, 2019-12-25


  • Assessment of Postoperative Renal Dysfunction Requiring Prolonged Renal Replacement Therapy and the Associated Mortality Rate

    Kogawa Rikizo , Ochiai Ryoichi

    … Following data were extracted from electronic patient records for analysis: preoperative renal function, incidence of RRT, recovery rate from RRT, and mortality rate at 6 months after surgery. … The mortality rate was 42.1% (67 of 159) in patients who required new RRT. … In multivariate analysis, the preoperative estimated glomerular filtration rate [adjusted OR = 0.76 (0.63-0.92), p = 0.005) was a significant risk factor for postoperative RRT dependence. …

    Toho journal of medicine 5(4), 173-178, 2019-12

    IR  DOI 

  • Age-Specific Impact of Atrial Fibrillation on Cardiovascular Mortality Among Japanese Men and Women (The Ibaraki Prefectural Health Study [IPHS])

    山岸 良匡 , Toshimi Sairenchi , Kazumasa YAMAGISHI , Hiroyasu Iso , Fujiko Irie , Ai Koba , Mitsumasa Umesawa , Yasuo Haruyama , Hiroshi Watanabe , Gen Kobashi , Hitoshi Ota

    … Hazard ratios for mortality stratified by gender and age groups were calculated using Cox's proportional hazards regression models. … On multivariable analysis, participants with AF had an increased risk of cardiovascular-related mortality compared with those without AF. … AF was significantly associated with all-cause mortality in each age and gender group; … AF may be an independent risk factor for cardiovascular and all-cause mortalities regardless of age. …

    The American Journal of Cardiology 124(9), 1413-1419, 2019-11


  • Relationship between Sedentary Behavior and All-cause Mortality in Japanese Chronic Hemodialysis Patients: A Prospective Cohort Study

    Hishii Shuhei , Miyatake Nobuyuki , Nishi Hiroyuki , Katayama Akihiko , Ujike Kazuhiro , Koumoto Kiichi , Suzuki Hiromi , Hashimoto Hiroo

    … We investigated the relationship between sedentary behavior and all-cause mortality in patients undergoing hemodialysis. … Sedentary behavior was thus an important factor for all-cause mortality even after adjusting for confounding factors by a Cox-proportional hazard model. …

    Acta Medica Okayama 73(5), 419-425, 2019-10

    IR  DOI 

  • Epidemiology of Chronic Obstructive Pulmonary Disease in Japan : Knowledge from Hisayama Study  [in Japanese]

    松元 幸一郎

    … Despite its high social and economic burden and mortality worldwide, its epidemiologic knowledge in Japan remained unestablished until the end of 20th century. … Subsequent analyses revealed that airflow obstruction is a significant risk factor for carotid atherosclerosis, especially in midlife, and deterioration of periodontal status could be a risk factor for rapid lung function decline. …

    福岡医学雑誌 = Fukuoka acta medica 110(1), 8-16, 2019-03-25

    IR  Ichushi Web 

  • AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus

    萩原 大祐 , Sanjoy Paul , Mark Stamnes , Grace Heredge Thomas , Hong Liu , Daisuke HAGIWARA , Katsuya Gomi , Scott G. Filler , W. Scott Moye-Rowley

    … Aspergillosis associated with azole-resistant Aspergillus fumigatus has a mortality rate that can approach 90% in certain patient populations. … Our previous studies identified a positively acting transcription factor called AtrR that binds to the promoter of cyp51A as well as that of an important membrane transporter protein gene called abcG1. …

    mBio 10(2), e02563-18, 2019-03


  • Lymphocyte Area Under the Curve as a Predictive Factor for Viral Infection after Allogenic Hematopoietic Stem Cell Transplantation

    Watanabe Mizuki , Kanda Junya , Hishizawa Masakatsu , Kondo Tadakazu , Yamashita Kouhei , Takaori-Kondo Akifumi

    … Viral infection is a serious complication that can greatly affect patient mortality and morbidity after allogenic hematopoietic stem cell transplantation (allo-HSCT). … For the early identification of patients at high risk for viral infection, we evaluated the impact of lymphocyte area under the curve (AUC) value as a new predictive factor for early immune reconstitution after allo-HSCT against viral infection. …

    Biology of Blood and Marrow Transplantation 25(3), 587-593, 2019-03


  • Atherosclerotic Heart Disease in Patients with Advanced Chronic Kidney Disease  [in Japanese]

    長谷 弘記

    … タチン,エリスロポエチン刺激剤,およびLDL-CおよびCRPの低下作用を有するレニン・アンジオテンシン受容体阻害剤の併用療法が,進行期CKD患者におけるASHD合併率を低下させることを報告した.しかしながら,血中リン酸塩低下療法がASHDを低下させるという報告は未だ報告されていないのが現状である.ABSTRACT: Atherosclerotic heart disease (ASHD) is a major contributor to morbidity and mortality in patients with chronic kidney disease (CKD), including …

    東邦医学会雑誌 = Journal of Medical Society of Toho University 66(1), 22-26, 2019-03

    IR  DOI  Ichushi Web 

  • Autophagy-Inducing Factor Atg1 Is Required for Virulence in the Pathogenic Fungus Candida glabrata

    Shimamura Shintaro , Miyazaki Taiga , Tashiro Masato , Takazono Takahiro , Saijo Tomomi , Yamamoto Kazuko , Imamura Yoshifumi , Izumikawa Koichi , Yanagihara Katsunori , Kohno Shigeru , Mukae Hiroshi

    … glabrata.A mutant strain lacking CgAtg1, an autophagy-inducing factor, was generated and confirmed to be deficient for autophagy. … Upon infecting mouse peritoneal macrophages, the Cgatg1Δ strain showed higher mortality from phagocytosis by macrophages. … glabrata virulence by conferring resistance to unstable nutrient environments and immune defense of hosts, and that Atg1 is a novel fitness factor in Candida species. …

    Frontiers in Microbiology (10), 27, 2019-01-25



    MORIKAWA Tomoki , ISERI Ken , INABA Taro , HAYASHI Junichi , SHIBATA Takanori

    維持血液透析(hemodialysis:HD)患者におけるエリスロポエチン治療に対する低反応性は生命予後不良との関連が報告されているが,HD導入期での検討は行われていない.今回,2011年4月から2016年3月の間に当院でHD導入となった322例を登録,除外基準に基づいて最終的に154例を対象とする後向きコホート研究を行った.1週間当たりの遺伝子組み換えヒトエリスロポエチン量(rHuEPO)を体重 …

    Journal of The Showa University Society 79(5), 627-635, 2019

    IR  J-STAGE 


    HAYASHI Junichi , ISERI Ken , INABA Taro , MORIKAWA Tomoki , SHIBATA Takanori

    慢性腎臓病(chronic kidney disease:CKD)患者では腎機能正常者と比較して感染症罹患時における予後が不良である.感染症を呈したCKD患者における生命予後を予測するモデルについてはこれまで検討されていない.本研究では,感染症に罹患したCKD患者における28日後の生命予後を予測する新たなスコアリングモデルの作成とその検証を目的とした後ろ向きコホート研究を行った.対象は,2015年 …

    Journal of The Showa University Society 79(5), 642-653, 2019

    IR  J-STAGE 

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